Preprint Case Report Version 1 Preserved in Portico This version is not peer-reviewed

Review into the Insights of the Immune System and Genome of the Marsupials. A Case Presentation of a West Indian Opossum (Didelphis marsupialis) with Leukopenia and Bacterial Infections.

Version 1 : Received: 7 February 2024 / Approved: 8 February 2024 / Online: 8 February 2024 (09:40:29 CET)

How to cite: Vaillant, A.; Soodeen, S.; Gopaul, D.; Arozarena-Fundora, R. Review into the Insights of the Immune System and Genome of the Marsupials. A Case Presentation of a West Indian Opossum (Didelphis marsupialis) with Leukopenia and Bacterial Infections.. Preprints 2024, 2024020469. https://doi.org/10.20944/preprints202402.0469.v1 Vaillant, A.; Soodeen, S.; Gopaul, D.; Arozarena-Fundora, R. Review into the Insights of the Immune System and Genome of the Marsupials. A Case Presentation of a West Indian Opossum (Didelphis marsupialis) with Leukopenia and Bacterial Infections.. Preprints 2024, 2024020469. https://doi.org/10.20944/preprints202402.0469.v1

Abstract

Opossums, native to the Americas, are unique marsupials with over 100 species. The Common Opossum and Virginia Opossum are notable species. They are nocturnal, omnivorous, and adapt to various habitats. Their reproduction involves a short gestation and marsupial pouch development. Despite their ecological benefits like seed dispersal and insect control, their proximity to human habitats exposes them to pathogens, posing public health risks. These include protozoa, helminths, and arthropods that can spread zoonotic parasites and vector-borne diseases. The marsupial immune system, including opossums, is complex, rivaling eutherian mammals. Key immune genes were identified in the grey short-tailed opossum genome. CD1 protein and VpreB surrogate light chain were also found. Marsupials are proposed as ideal models for studying developmental immunology. A West Indian opossum (Didelphis marsupialis) was found and examined. Blood tests revealed abnormalities, including a low white blood cell count and signs of anemia. The results contribute to understanding the species’ health and adaptability in the wild.

Keywords

Opossum; Marsupials; immune system; biochemistry; genome; bacterial diseases; leukopaenia; anaemia

Subject

Biology and Life Sciences, Immunology and Microbiology

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