Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Quercetin, A Flavonoid With Great Pharmacological Capacity

Eber Josue Carrillo-Martinez
,
Flor Yohana Flores-Hernández
ORCID logo ,
Adriana María Salazar-Montes
,
Hector Fabián Nario-Chaidez
,
Luis Daniel Hernández-Ortega
*
Version 1 : Received: 1 February 2024 / Approved: 1 February 2024 / Online: 2 February 2024 (06:36:16 CET)

A peer-reviewed article of this Preprint also exists.

Carrillo-Martinez, E.J.; Flores-Hernández, F.Y.; Salazar-Montes, A.M.; Nario-Chaidez, H.F.; Hernández-Ortega, L.D. Quercetin, a Flavonoid with Great Pharmacological Capacity. Molecules 2024, 29, 1000. Carrillo-Martinez, E.J.; Flores-Hernández, F.Y.; Salazar-Montes, A.M.; Nario-Chaidez, H.F.; Hernández-Ortega, L.D. Quercetin, a Flavonoid with Great Pharmacological Capacity. Molecules 2024, 29, 1000.

Abstract

Quercetin is a flavonoid with a low molecular weight that belongs to the human diet's phenolic phytochemicals and non-energy constituents. Quercetin has a potent antioxidant capacity, being able to capture Reactive Oxygen Species (ROS), reactive nitro-gen species (RNS), and Reactive Chlorine Species (ROC), which act as reducing agents by chelating transition metal ions. Its structure has five functional hydroxyl groups, which work as electron donors and are responsible for capturing free radicals. In addition to its antioxidant capacity, it was described different pharmacological properties of Quercetin, such as carcinostatic properties, antiviral, antihypertensive, anti-inflammatory, protection of Low-Density Lipoprotein (LDL) oxidation, and inhibi-tion of angiogenesis are developed in this review.

Keywords

Quercetin; Antioxidant; Free radicals; Pharmacological properties; Nanoparticles

Subject

Medicine and Pharmacology, Pharmacology and Toxicology

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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