Version 1
: Received: 18 January 2024 / Approved: 23 January 2024 / Online: 23 January 2024 (10:53:46 CET)
How to cite:
Parker, R.G.; Shou, J.; Woods, C.; Lambert, N.; Barrett, T. Umbilical Cord Connective Tissue Allograft Applications with EPAT and Class IV Lasers for Defects of the Plantar Fascia: A Case Series. Preprints2024, 2024011687. https://doi.org/10.20944/preprints202401.1687.v1
Parker, R.G.; Shou, J.; Woods, C.; Lambert, N.; Barrett, T. Umbilical Cord Connective Tissue Allograft Applications with EPAT and Class IV Lasers for Defects of the Plantar Fascia: A Case Series. Preprints 2024, 2024011687. https://doi.org/10.20944/preprints202401.1687.v1
Parker, R.G.; Shou, J.; Woods, C.; Lambert, N.; Barrett, T. Umbilical Cord Connective Tissue Allograft Applications with EPAT and Class IV Lasers for Defects of the Plantar Fascia: A Case Series. Preprints2024, 2024011687. https://doi.org/10.20944/preprints202401.1687.v1
APA Style
Parker, R.G., Shou, J., Woods, C., Lambert, N., & Barrett, T. (2024). Umbilical Cord Connective Tissue Allograft Applications with EPAT and Class IV Lasers for Defects of the Plantar Fascia: A Case Series. Preprints. https://doi.org/10.20944/preprints202401.1687.v1
Chicago/Turabian Style
Parker, R.G., Naomi Lambert and Tyler Barrett. 2024 "Umbilical Cord Connective Tissue Allograft Applications with EPAT and Class IV Lasers for Defects of the Plantar Fascia: A Case Series" Preprints. https://doi.org/10.20944/preprints202401.1687.v1
Abstract
Foot pain related to the plantar fascia is common in adults regardless of athletic background. Many pathologies can lead to the diagnosis of plantar enthesopathy, but the most relevant to this case study is related to structural defects within the plantar fascia. Due to the variety and sometimes unclear etiology of plantar fasciosis, no single standard of care treatment protocol is recognized. Often, patients receive NSAIDs, night splints, taping, physical therapy, foot orthosis, and extracorporeal shock wave therapies. This study presents Wharton Jelly (WJ) tissue allografts as an additional intervention for patients who fail standard-care treatments. WJ allografts are applied to supplement connective tissue defects directly, unlike other therapies, which aim to reduce swelling and symptomatic pain. This retrospective study includes seven patients who have previously failed standard-of-care treatment. Each received extracorporeal pulse-activated therapy (EPAT), WJ, laser therapy, and an orthotic. Patient progress was tracked using a visual analog scale, 0-10 scoring, reported by the patient at the initial visit and approximately thirteen weeks following, reporting an average improvement of 50%. The study's limitations include a small cohort size and a non-blinded retrospective design. These promising results provide evidence for a more extensive, randomized study to define dosage protocols further and confirm safety and efficacy.
Keywords
Plantar Fasciosis; Enthesopathies; Wharton’s Jelly; laser therapy; EPAT; Regenerative Medicine
Subject
Medicine and Pharmacology, Orthopedics and Sports Medicine
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.