Integrating a Fundus Camera with High Frequency Ultrasound for Precise Ocular Lesion Assessment

Alfa Rossi; Yushun Zeng; Mojtaba Rahimi; Taeyoon Son; Michael J. Heiferman; Chen Gong; Xin Sun; Mohammad Soleimani; Ali R. Djalilian; Mark S. Humayun; Qifa Zhou; Xincheng Yao

doi:10.20944/preprints202401.1220.v1

A peer-reviewed article of this Preprint also exists.

Rossi, A.; Zeng, Y.; Rahimi, M.; Son, T.; Heiferman, M.J.; Gong, C.; Sun, X.; Soleimani, M.; Djalilian, A.R.; Humayun, M.S.; Zhou, Q.; Yao, X. Integrating a Fundus Camera with High-Frequency Ultrasound for Precise Ocular Lesion Assessment. Biosensors 2024, 14, 127. Rossi, A.; Zeng, Y.; Rahimi, M.; Son, T.; Heiferman, M.J.; Gong, C.; Sun, X.; Soleimani, M.; Djalilian, A.R.; Humayun, M.S.; Zhou, Q.; Yao, X. Integrating a Fundus Camera with High-Frequency Ultrasound for Precise Ocular Lesion Assessment. Biosensors 2024, 14, 127.

Abstract

Ultrasound A-scan is an important tool for quantitative assessment of ocular lesions. However, its usability is limited by difficulty to accurately localize the ultrasound probe to a lesion of interest. In this study, a transparent LiNbO3 single crystal ultrasound transducer was fabricated, and integrated with a widefield fundus camera to guide the ultrasound local position. The novel fundus camera guided ultrasound probe was validated for in vivo measurement of rat eyes. Anterior and posterior segments of the rat eye could be unambiguously differentiated with the fundus photography guided ultrasound measurement. A model eye was also used to verify the clinical potential of the prototype device.

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Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Integrating a Fundus Camera with High Frequency Ultrasound for Precise Ocular Lesion Assessment

Abstract

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Subject

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