Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

The Economic Burden of Atopic Dermatitis in Romania: A Broad Perspective

Version 1 : Received: 9 January 2024 / Approved: 10 January 2024 / Online: 10 January 2024 (12:02:23 CET)
Version 2 : Received: 15 January 2024 / Approved: 16 January 2024 / Online: 16 January 2024 (10:29:04 CET)

How to cite: Nicolescu, A.C.; Strilciuc, S.; Lapadatu, R.; Grad, D.A.; Vladescu, C.; Olteanu, R. The Economic Burden of Atopic Dermatitis in Romania: A Broad Perspective. Preprints 2024, 2024010830. https://doi.org/10.20944/preprints202401.0830.v1 Nicolescu, A.C.; Strilciuc, S.; Lapadatu, R.; Grad, D.A.; Vladescu, C.; Olteanu, R. The Economic Burden of Atopic Dermatitis in Romania: A Broad Perspective. Preprints 2024, 2024010830. https://doi.org/10.20944/preprints202401.0830.v1

Abstract

Background: Atopic dermatitis (AD), a common dermatological condition, is often associated with significant economic and social burdens. Despite extensive studies globally, there is a gap in understanding the comprehensive impact of this condition in Romania. Objectives:This study evaluated the economic burden and quality of life impact of AD in Romania, considering both direct and indirect costs. Materials & Methods:A mixed-methods study was conducted from April to October 2023, involving 826 responses from AD patients and caregivers. Surveys, interviews, and national health data analysis were used to assess direct medical costs (treatments, medical services), direct non-medical costs (transportation, accommodation), and indirect costs (productivity losses). Quality of life was evaluated using the EuroQol EQ-5D-5L instrument. Results:The total cost of AD in Romania for 2021 was 30.418.896 EUR, with a significant proportion attributed to indirect costs. The average per-patient cost was approximately 164 EUR. The average cost per patient was 33 EUR (n=42.206) for mild cases, 355 EUR (n=110.160) for moderate cases, and 2448 EUR (n=33828) for severe cases. The data revealed a higher burden in patients with moderate to severe AD, predominantly female, with significant impacts on daily life and mental health. Conclusion:The expenditure on AD management in Romania is substantially lower compared to other countries, thus posing a significant economic burden, largely driven by indirect costs. This study provides a foundation for future policy interventions and highlights the need for targeted management strategies for AD.

Keywords

Atopic dermatitis, economic burden of disease, cost of illness

Subject

Medicine and Pharmacology, Dermatology

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