Version 1
: Received: 26 December 2023 / Approved: 10 January 2024 / Online: 10 January 2024 (09:46:27 CET)
How to cite:
Gusmão, A.B.D.; Albuquerque, P.B.S.D.; Correia, A.C.D.C. Use of Metallic Nanoparticles Synthesized from Plant Extracts in the Wound Healing – a Review. Preprints2024, 2024010770. https://doi.org/10.20944/preprints202401.0770.v1
Gusmão, A.B.D.; Albuquerque, P.B.S.D.; Correia, A.C.D.C. Use of Metallic Nanoparticles Synthesized from Plant Extracts in the Wound Healing – a Review. Preprints 2024, 2024010770. https://doi.org/10.20944/preprints202401.0770.v1
Gusmão, A.B.D.; Albuquerque, P.B.S.D.; Correia, A.C.D.C. Use of Metallic Nanoparticles Synthesized from Plant Extracts in the Wound Healing – a Review. Preprints2024, 2024010770. https://doi.org/10.20944/preprints202401.0770.v1
APA Style
Gusmão, A.B.D., Albuquerque, P.B.S.D., & Correia, A.C.D.C. (2024). Use of Metallic Nanoparticles Synthesized from Plant Extracts in the Wound Healing – a Review. Preprints. https://doi.org/10.20944/preprints202401.0770.v1
Chicago/Turabian Style
Gusmão, A.B.D., Priscilla Barbosa Sales de Albuquerque and Ana Carolina de Carvalho Correia. 2024 "Use of Metallic Nanoparticles Synthesized from Plant Extracts in the Wound Healing – a Review" Preprints. https://doi.org/10.20944/preprints202401.0770.v1
Abstract
Wound healing is rarely seen as a problem in healthy individuals; however, under certain pathophysiological conditions, this process can be impaired, leading to the emergence of chronic wounds, which are themselves a serious public health problem. This work aimed to review the most important and recent literature on the use of metallic nanoparticles, in this case those produced from plant extracts, and their application as healing agents. For this, we firstly provided an insight into the pathophysiology of the wound healing process and then the main routes for obtaining metallic nanoparticles. The methodology of synthesis, which is part of the so-called green synthesis, has been the subject of several studies reporting the use of medicinal plants as subtracts for the production of different nanoparticles (of silver, gold, and zinc). Additionally, their use as wound healing agents is close related with biological properties such as antimicrobial, anti-inflammatory, and healing. Finally, we addressed in vitro and in vivo studies reporting the efficiency of metallic nanoparticles synthesized with plant extracts and applied in different pharmaceutical forms on the wound healing process. Based on these satisfactory results, we verified that metallic nanoparticles are potential therapeutic alternatives when compared to the traditional synthetic healing agents, thus foreseeing the production of new drugs in the pharmaceutical market.
Medicine and Pharmacology, Pharmacology and Toxicology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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