Version 1
: Received: 2 January 2024 / Approved: 3 January 2024 / Online: 3 January 2024 (09:43:18 CET)
How to cite:
Chaudhary, R.; Vyas, T.; Patel, P.; Parmar, K. Neurological Conundrums: Delving into the Complexities of Neuromyelitis Optica Spectrum Disorder with a Detailed Case Analysis. Preprints2024, 2024010224. https://doi.org/10.20944/preprints202401.0224.v1
Chaudhary, R.; Vyas, T.; Patel, P.; Parmar, K. Neurological Conundrums: Delving into the Complexities of Neuromyelitis Optica Spectrum Disorder with a Detailed Case Analysis. Preprints 2024, 2024010224. https://doi.org/10.20944/preprints202401.0224.v1
Chaudhary, R.; Vyas, T.; Patel, P.; Parmar, K. Neurological Conundrums: Delving into the Complexities of Neuromyelitis Optica Spectrum Disorder with a Detailed Case Analysis. Preprints2024, 2024010224. https://doi.org/10.20944/preprints202401.0224.v1
APA Style
Chaudhary, R., Vyas, T., Patel, P., & Parmar, K. (2024). Neurological Conundrums: Delving into the Complexities of Neuromyelitis Optica Spectrum Disorder with a Detailed Case Analysis. Preprints. https://doi.org/10.20944/preprints202401.0224.v1
Chicago/Turabian Style
Chaudhary, R., Param Patel and Kartikeya Parmar. 2024 "Neurological Conundrums: Delving into the Complexities of Neuromyelitis Optica Spectrum Disorder with a Detailed Case Analysis" Preprints. https://doi.org/10.20944/preprints202401.0224.v1
Abstract
Neuromyelitis optica spectrum disorder (NMOSD), previously known as Devic disease or neuromyelitis optica (NMO), represents inflammatory conditions affecting the central nervous system. These disorders are characterized by severe immune-mediated demyelination and axonal damage, with a predilection for targeting optic nerves and the spinal cord. Key clinical features of NMOSD encompass acute episodes of bilateral or rapid sequential optic neuritis and transverse myelitis, typically exhibiting a relapsing course. These attacks endure for several days, and recovery varies, spanning from weeks to months. In this report, we present the case of a 35-year-old individual who initially complained of urinary retention, followed by decreasing vision in the left eye and subsequently in the right eye. These visual symptoms were succeeded by weakness in the right upper and lower limbs.
Keywords
Neuromyelitis optica spectrum disorder (NMOSD); Aquaporin proteins; AQP4 and AQP1; longitudinally extensive transverse myelitis (LETM); Area Postrema Syndrome
Subject
Medicine and Pharmacology, Neuroscience and Neurology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
