Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Circuit training improves the levels of Aβ and BDNF related to cognitive impairment risk factors in obese elderly Korean women

Version 1 : Received: 22 December 2023 / Approved: 22 December 2023 / Online: 22 December 2023 (10:20:35 CET)

A peer-reviewed article of this Preprint also exists.

Kang, D.; Koh, S.; Kim, T.; Bressel, E.; Kim, D. Circuit Training Improves the Levels of β-Amyloid and Brain-Derived Neurotrophic Factor Related to Cognitive Impairment Risk Factors in Obese Elderly Korean Women. J. Clin. Med. 2024, 13, 799. Kang, D.; Koh, S.; Kim, T.; Bressel, E.; Kim, D. Circuit Training Improves the Levels of β-Amyloid and Brain-Derived Neurotrophic Factor Related to Cognitive Impairment Risk Factors in Obese Elderly Korean Women. J. Clin. Med. 2024, 13, 799.

Abstract

The purpose of this study was to investigate the effect of circuit training on β-amyloid, BDNF, and cognitive function in untrained obese elderly Korean women. The subjects for the study were aged 65–70 years, composed of the circuit training group(n=12) and control group(n=11). The 60-minute combined exercise was performed 3 times per week for 16 weeks. Exercise intensity was progressively increased from 40% HRR to 70% HRR. The test data were analyzed by paired t-test, independent t-test, and two-way repeated measures ANOVA, and the alpha level of .05 was set for all tests of significance. The findings of this study were as follows: β-amyloid significantly decreased after the exercise group had compared to before the exercise and BDNF and cognitive function significantly increased after the exercise group had compared to before the exercise. However, there were no significant changes in β-amyloid, BDNF, and cognitive function in the control group Therefore, it is suggested that the circuit training used in this study could be an effective exercise method for improving the risk factors of cognitive impairment in obese elderly Korean women.

Keywords

circuit training; β-amyloid; BDNF; cognitive function; obese elderly women

Subject

Medicine and Pharmacology, Clinical Medicine

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