Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

What’s New about Parsley, a Potential Source of Cardioprotective Therapeutic Substances?

Version 1 : Received: 20 December 2023 / Approved: 21 December 2023 / Online: 21 December 2023 (11:48:11 CET)

A peer-reviewed article of this Preprint also exists.

Casanova, L.M.; dos Santos Nascimento, L.B.; Costa, S.S. What Is New about Parsley, a Potential Source of Cardioprotective Therapeutic Substances? Nutraceuticals 2024, 4, 104-126. Casanova, L.M.; dos Santos Nascimento, L.B.; Costa, S.S. What Is New about Parsley, a Potential Source of Cardioprotective Therapeutic Substances? Nutraceuticals 2024, 4, 104-126.

Abstract

Petroselinum crispum (Mill.) Fuss (Apiaceae), popularly known as parsley, is a ubiquitous aromatic herb used for culinary and medicinal purposes worldwide. Besides the richness in nutrients, sev-eral bioactive secondary metabolites, especially the flavone apigenin and its glycosides, have been described in the species. Parsley has already been shown to have several health-promoting activi-ties, such as antithrombotic, antihypertensive, and hypolipidemic. The multiple studies conducted in animal models so far suggest the species is a potential source of cardioprotective agents. This review provides up to date information and perspectives on the potential of parsley and its bioac-tive compounds for the development of nutraceutical products and drugs for the promotion of cardiovascular health. It includes not only a discussion on reported bioactivities, but also the knowledge of supplements and food additives developed as innovative parsley-based products.

Keywords

Petroselinum crispum; culinary herbs; antithrombotic activity; antihypertensive activity; hypolipidemic activity; cardiovascular health; nutraceutical; phytotherapy; apigenin glycosides.

Subject

Medicine and Pharmacology, Cardiac and Cardiovascular Systems

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