Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Design Flaws Unveiled: The Risk of Autoimmunity from Defective RNA Reading Frames in Pfizer's ModRNA COVID-19 Vaccine

Version 1 : Received: 19 December 2023 / Approved: 20 December 2023 / Online: 20 December 2023 (09:42:07 CET)

How to cite: Palacios- Castrillo, R. Design Flaws Unveiled: The Risk of Autoimmunity from Defective RNA Reading Frames in Pfizer's ModRNA COVID-19 Vaccine. Preprints 2023, 2023121502. https://doi.org/10.20944/preprints202312.1502.v1 Palacios- Castrillo, R. Design Flaws Unveiled: The Risk of Autoimmunity from Defective RNA Reading Frames in Pfizer's ModRNA COVID-19 Vaccine. Preprints 2023, 2023121502. https://doi.org/10.20944/preprints202312.1502.v1

Abstract

Recently, Mulroney,et.al., demonstrated that Pfizer’s ModRNA Covid vaccine, but not AstraZeneca Covid vaccine, produce aberrant foreign proteins in vivo due to reading frame shift in ribosomes. This phenomenon could elucidate the notable surge in autoimmune diseases following the administration of ModRNA vaccines compared to Influenza vaccines between 2020 and 2023, as found in the VAERS database. These findings bear significant implications for the future application of mRNA technology, emphasizing the necessity of modifying the design of the mRNA sequence to mitigate these defects. Remarkably, Mulroney and collaborators achieved a reduction in frame shift proteins by introducing additional edits to the mRNA sequences. This adjustment is pivotal for rectifying the flawed design of the ModRNA employed by Pfizer. In light of these findings, many advocate for the immediate recall and further investigation of these products. The notion of a "future mRNA-based therapy" should be postponed indefinitely.

Keywords

ModRNA vaccines trigger autoimmune disorders, Autoimmunity, serious side effects of Covid-19 ModRNA vaccines ,vaccine induced autoimmunity. 

Subject

Biology and Life Sciences, Biology and Biotechnology

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