Preprint Case Report Version 1 Preserved in Portico This version is not peer-reviewed

Refractory Electrical Storm after Acute Myocardial Infarction: The Role of Temporary Ventricular Overdrive Pacing as a Bridge to ICD Implantation

Version 1 : Received: 18 December 2023 / Approved: 19 December 2023 / Online: 19 December 2023 (09:05:02 CET)

A peer-reviewed article of this Preprint also exists.

Meter, M.; Borovac, J.A. A Refractory Electrical Storm after Acute Myocardial Infarction: The Role of Temporary Ventricular Overdrive Pacing as a Bridge to ICD Implantation. Pathophysiology 2024, 31, 44-51. Meter, M.; Borovac, J.A. A Refractory Electrical Storm after Acute Myocardial Infarction: The Role of Temporary Ventricular Overdrive Pacing as a Bridge to ICD Implantation. Pathophysiology 2024, 31, 44-51.

Abstract

Electrical storm (ES) is defined as the presence of at least three episodes of sustained ventricular tachycardia or ventricular fibrillation within 24 hours. This patient had a previously known arterial hypertension, type II diabetes mellitus, and chronic kidney disease and has presented to the Emergency Department (ED) with symptoms of retrosternal chest pain lasting for several hours prior. The initial 12-lead electrocardiogram revealed ST segment elevation in the anterior leads (V1-V6). Emergent coronary angiography revealed an acute occlusion of the proximal left anterior descending artery (pLAD) and percutaneous coronary intervention was performed with successful implantation of one drug-eluting stent in the pLAD. On the day 8 of hospitalization, patient developed a refractory ES for which he received 50 DC shocks and did not respond to multiple lines of antiarrhythmic medications. Due to a failure of medical therapy, we decided to implant a temporary pacemaker and initiate ventricular overdrive pacing (VOP) that was successful in terminating ES. Following electrical stabilization, the patient underwent a successful ICD implantation. This case demonstrates that VOP can contribute to hemodynamic and electrical stabilization of a patient that suffers from refractory ES and this treatment modality might serve as a temporary bridge to ICD implantation.

Keywords

acute coronary syndrome; electrical storm; case report; antiarrhythmic therapy; ventricular overdrive pacing; VOP; ICD; myocardial infarction; bridge-to-ICD; medical management

Subject

Medicine and Pharmacology, Cardiac and Cardiovascular Systems

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