Version 1
: Received: 11 December 2023 / Approved: 13 December 2023 / Online: 13 December 2023 (11:29:13 CET)
How to cite:
Gincheva, D. H.; Gorchev, G. A.; Vanov, A. V.; Gincheva, V. H. Aggressive Аngiomyxoma of the Female External Genitalia - A Rare Clinical Case. Preprints2023, 2023120985. https://doi.org/10.20944/preprints202312.0985.v1
Gincheva, D. H.; Gorchev, G. A.; Vanov, A. V.; Gincheva, V. H. Aggressive Аngiomyxoma of the Female External Genitalia - A Rare Clinical Case. Preprints 2023, 2023120985. https://doi.org/10.20944/preprints202312.0985.v1
Gincheva, D. H.; Gorchev, G. A.; Vanov, A. V.; Gincheva, V. H. Aggressive Аngiomyxoma of the Female External Genitalia - A Rare Clinical Case. Preprints2023, 2023120985. https://doi.org/10.20944/preprints202312.0985.v1
APA Style
Gincheva, D. H., Gorchev, G. A., Vanov, A. V., & Gincheva, V. H. (2023). Aggressive Аngiomyxoma of the Female External Genitalia - A Rare Clinical Case. Preprints. https://doi.org/10.20944/preprints202312.0985.v1
Chicago/Turabian Style
Gincheva, D. H., Aleksandar Vanov Vanov and Veronika Hristova Gincheva. 2023 "Aggressive Аngiomyxoma of the Female External Genitalia - A Rare Clinical Case" Preprints. https://doi.org/10.20944/preprints202312.0985.v1
Abstract
Aggressive angiomyxoma (AAM) is a rare and benign mesenchymal tumor, localized predominantly in the female pelvis. Its invasive growth and local recurrence are challenging for professionals. Histologically, AAM is a tumor with a myxoid, highly vascularized stroma. The diagnosis is made relatively late due to nonspecific symptoms. Treatment of AAM is extensive local surgical excision. Gonadotropin-releasing hormone agonists are added postoperatively. The prognosis is good and metastasis is rare.
We present a case of an AAM located in the left greater labial area in a 50-year-old woman initially diagnosed as left inguinal hernia.
The tumor was extirpated under epidural anaesthesia on the date of the patient's informed consent.
The patient was prescribed postoperative therapy with Zoladex 3,6 mg according to the schedule. The patient was subjected to monthly gynecological check-ups for one year after the surgical intervention. To date, no recurrence of the underlying disease has been detected. Long-term results show a good trend.
In conclusion, we can say that the optimal treatment of AAM is wide local excision. Рadicality is not recommended because of the risk of postoperative complications. Postoperative administration of GnRH-a is advisable to avoid recurrences. All patients undergo regular follow-up examinations for long-term.
Keywords
aggressive angiomyxoma; soft tissue tumors
Subject
Medicine and Pharmacology, Clinical Medicine
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
