Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

The Varied Impacts of Vascular Endothelial Growth Factor-a (VEGF-a) on Vasculature in Ovarian Hyper Stimulation Syndrome (OHSS) and Obesity

Version 1 : Received: 5 December 2023 / Approved: 6 December 2023 / Online: 7 December 2023 (14:58:43 CET)

How to cite: Rahimianfar, F.; Rahimianfar, M.; Eshghjoo, S. The Varied Impacts of Vascular Endothelial Growth Factor-a (VEGF-a) on Vasculature in Ovarian Hyper Stimulation Syndrome (OHSS) and Obesity. Preprints 2023, 2023120433. https://doi.org/10.20944/preprints202312.0433.v1 Rahimianfar, F.; Rahimianfar, M.; Eshghjoo, S. The Varied Impacts of Vascular Endothelial Growth Factor-a (VEGF-a) on Vasculature in Ovarian Hyper Stimulation Syndrome (OHSS) and Obesity. Preprints 2023, 2023120433. https://doi.org/10.20944/preprints202312.0433.v1

Abstract

Vascular endothelial growth factors (VEGFs) are regarded as the key vasculogenic mediators in the human body, of which VEGF-A is considered as one of the important types. It is the major growth factor possessing increasing vascular permeability as well as angiogenesis properties. This article provides intuition into the different effects of VEGF-A on vessels in ovarian hyper stimulation syndrome (OHSS) which is defined as a complication of in-vitro fertilization for infertility treatment, and obesity, a universally health problem. These are two dissimilar pathways outcomes for VEGF-A effects, thereby This article reviews updated information about the mentioned disorders and reveals that how this kind of growth factor yields different results on vasculature by activating distinct intracellular signaling in endothelial cells.

Keywords

obesity; VEGF-A; vascular permeability; ovarian hyper stimulation syndrome; adipose tissue; angiogenesis; adipocytes; endothelial cell; IVF; infertility

Subject

Medicine and Pharmacology, Obstetrics and Gynaecology

Comments (0)

We encourage comments and feedback from a broad range of readers. See criteria for comments and our Diversity statement.

Leave a public comment
Send a private comment to the author(s)
* All users must log in before leaving a comment
Views 0
Downloads 0
Comments 0
Metrics 0


×
Alerts
Notify me about updates to this article or when a peer-reviewed version is published.
We use cookies on our website to ensure you get the best experience.
Read more about our cookies here.