Version 1
: Received: 4 December 2023 / Approved: 6 December 2023 / Online: 6 December 2023 (12:15:38 CET)
How to cite:
Kristo, N.; Verdes, G.; Faur, I. F.; Hordovan, E. C.; Duta, C. Presentation and Surgical Management of Perineal Hidradenitis Suppurativa and Langerhans Cell Histiocytosis. Preprints2023, 2023120401. https://doi.org/10.20944/preprints202312.0401.v1
Kristo, N.; Verdes, G.; Faur, I. F.; Hordovan, E. C.; Duta, C. Presentation and Surgical Management of Perineal Hidradenitis Suppurativa and Langerhans Cell Histiocytosis. Preprints 2023, 2023120401. https://doi.org/10.20944/preprints202312.0401.v1
Kristo, N.; Verdes, G.; Faur, I. F.; Hordovan, E. C.; Duta, C. Presentation and Surgical Management of Perineal Hidradenitis Suppurativa and Langerhans Cell Histiocytosis. Preprints2023, 2023120401. https://doi.org/10.20944/preprints202312.0401.v1
APA Style
Kristo, N., Verdes, G., Faur, I. F., Hordovan, E. C., & Duta, C. (2023). Presentation and Surgical Management of Perineal Hidradenitis Suppurativa and Langerhans Cell Histiocytosis. Preprints. https://doi.org/10.20944/preprints202312.0401.v1
Chicago/Turabian Style
Kristo, N., Eniko Christine Hordovan and Ciprian Duta. 2023 "Presentation and Surgical Management of Perineal Hidradenitis Suppurativa and Langerhans Cell Histiocytosis" Preprints. https://doi.org/10.20944/preprints202312.0401.v1
Abstract
Hidradenitis suppurativa and Langerhans cell histiocytosis are rare disorders that can reveal similar clinical manifestations, making differential diagnosis difficult. A definitive diagnosis requires biopsy and histological confirmation in suspicious cases. The complex pathophysiology of these diseases has still not been understood, therefore the treatment is still a challenge for physicians. It is seen with predilection in the intertriginous areas of the body, predominantly in the axillary region, rarely requiring a surgical procedure. However perineal, perianal, and gluteal HS usually necessitates some form of surgical treatment. Langerhans cell histiocytosis (histiocytosis X) is a very rare systemic disease manifested by clonal cell proliferation of histiocytic-dendritic nature, with pseudonodular manifestation that deeply infiltrates the hypodermis and ulcerates the epidermis on the surface. Langerhans cells are dendritic, antigen-presenting cells localized in the suprabasal regions of the squamous epithelium of the skin and mucous membranes, which help regulate the immune system. In this report, we present our experience with extensive gluteal, perineal, and perianal hidradenitis suppurativa and Langerhans cell histiocytosis cases, including our treatment methods and outcomes.
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
