Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Formulation and Characterization of a Microencapsulant of Sungkai Leaves Ethanol Extract (Peronema canescens Jack)

Version 1 : Received: 27 November 2023 / Approved: 28 November 2023 / Online: 29 November 2023 (07:48:53 CET)

How to cite: Tarigan, I.L.; Farah, F.; Puspitasari, R.D.; Latief, M. Formulation and Characterization of a Microencapsulant of Sungkai Leaves Ethanol Extract (Peronema canescens Jack). Preprints 2023, 2023111821. https://doi.org/10.20944/preprints202311.1821.v1 Tarigan, I.L.; Farah, F.; Puspitasari, R.D.; Latief, M. Formulation and Characterization of a Microencapsulant of Sungkai Leaves Ethanol Extract (Peronema canescens Jack). Preprints 2023, 2023111821. https://doi.org/10.20944/preprints202311.1821.v1

Abstract

Background: Sungkai plant (Peronema canescens Jack.) is one of the medicinal plants widely grown in Indonesia. In recent years, Sungkai (Peronema canescens Jack) leaves have sparked particular interest for their health benefits. In this study, microencapsulation was conducted on an ethanol extract of Sungkai leaves (Peronema canescens Jack.) using three types of coating materials (maltodextrin, inulin, and Arabic gum) at various concentrations. Objectives: to determine the best microencapsulation formulation using maltodextrin, inulin, and Arabic gum at various concentrations.  Methods: Microencapsulation was performed using the extrusion method. Characterization of the best microencapsulant was done by measuring physico-chemical, morphological, and IR properties, and antioxidant activity testing was done using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) method. Results: Microencapsulant A1 has better physico-chemical properties compared to other microencapsulant samples. The results of the morphological analysis of sample A1 using SEM showed a smooth surface with a slightly round shape, as well as minimal wall folds and cracks, indicating that the product has good stability. The results of the functional group analysis of sample A1 using FTIR also showed that the ethanol extract of Sungkai leaves was well encapsulated. Conclusions: The best formulation to make microencapsulant of ethanol extract of Sungkai leaves is formulation A1 using Arabic gum dressing material.

Keywords

Peronema canescens Jack; Microencapsulation; Maltodextrin; Arabic gum; Inulin

Subject

Medicine and Pharmacology, Medicine and Pharmacology

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