PreprintArticleVersion 1Preserved in Portico This version is not peer-reviewed
Effects of Supplementation with Lutein Plus Docosahexaenoic Acid Oral Complex on Eye Dryness, Visual Function, and Memory Function in Healthy Subjects: A Single‐Arm Clinical Trial
Version 1
: Received: 24 November 2023 / Approved: 24 November 2023 / Online: 27 November 2023 (07:18:12 CET)
How to cite:
Hsu, L.; Huang, E.J.C.; Chien, Y. Effects of Supplementation with Lutein Plus Docosahexaenoic Acid Oral Complex on Eye Dryness, Visual Function, and Memory Function in Healthy Subjects: A Single‐Arm Clinical Trial. Preprints2023, 2023111609. https://doi.org/10.20944/preprints202311.1609.v1
Hsu, L.; Huang, E.J.C.; Chien, Y. Effects of Supplementation with Lutein Plus Docosahexaenoic Acid Oral Complex on Eye Dryness, Visual Function, and Memory Function in Healthy Subjects: A Single‐Arm Clinical Trial. Preprints 2023, 2023111609. https://doi.org/10.20944/preprints202311.1609.v1
Hsu, L.; Huang, E.J.C.; Chien, Y. Effects of Supplementation with Lutein Plus Docosahexaenoic Acid Oral Complex on Eye Dryness, Visual Function, and Memory Function in Healthy Subjects: A Single‐Arm Clinical Trial. Preprints2023, 2023111609. https://doi.org/10.20944/preprints202311.1609.v1
APA Style
Hsu, L., Huang, E.J.C., & Chien, Y. (2023). Effects of Supplementation with Lutein Plus Docosahexaenoic Acid Oral Complex on Eye Dryness, Visual Function, and Memory Function in Healthy Subjects: A Single‐Arm Clinical Trial. Preprints. https://doi.org/10.20944/preprints202311.1609.v1
Chicago/Turabian Style
Hsu, L., Evelyn Jou Chen Huang and Yi-Wen Chien. 2023 "Effects of Supplementation with Lutein Plus Docosahexaenoic Acid Oral Complex on Eye Dryness, Visual Function, and Memory Function in Healthy Subjects: A Single‐Arm Clinical Trial" Preprints. https://doi.org/10.20944/preprints202311.1609.v1
Abstract
Dry eye syndrome (DES) has become increasingly prevalent due to the prolonged use of digital devices in modern society. Individual supplementation with lutein or docosahexaenoic acid (DHA) demonstrated potential benefits for eye health. This study aimed to investigate the effects of lutein plus DHA complex supplementation on DES, visual function, and memory in healthy individuals. Thirty-four participants, aged 40~60 years, received lutein/DHA complex supplements (containing 10 mg free-form lutein, 200 mg DHA, 30 mg red algae extract (astaxanthin), phosphatidylserine, and vitamin A) for 12 weeks. Ophthalmological examinations and memory tests were carried out, and a questionnaire was administered at weeks 0, 6, and 12 of the study. After 12 weeks of the intervention, the tear break-up time had significantly increased, and intraocular pressure (IOP) had significantly decreased. This suggests that lutein/DHA complex supplementation may reduce the IOP and offer potential benefits for DES, as indicated by improved tear stability.
Keywords
lutein; docosahexaenoic acid; dry eye syndrome; visual function; memory function
Subject
Biology and Life Sciences, Food Science and Technology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
