Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Red Blood Cell Distribution Width, Erythrocyte Indices and Elongation Index, at Baseline, in a Group of Trained Subjects

Version 1 : Received: 22 November 2023 / Approved: 24 November 2023 / Online: 26 November 2023 (05:59:31 CET)

A peer-reviewed article of this Preprint also exists.

Caimi, G.; Carlisi, M.; Presti, R.L. Red Blood Cell Distribution Width, Erythrocyte Indices, and Elongation Index at Baseline in a Group of Trained Subjects. J. Clin. Med. 2024, 13, 151. Caimi, G.; Carlisi, M.; Presti, R.L. Red Blood Cell Distribution Width, Erythrocyte Indices, and Elongation Index at Baseline in a Group of Trained Subjects. J. Clin. Med. 2024, 13, 151.

Abstract

. Background: regular exercise elicits adaptive changes from several organs and physiological processes, including erythrocyte properties. Methods: in a group of 79 subjects (62 men and 17 women; mean age 31.37 +/- 10.19 years) who trained several times a week as they practiced amateur sports, we evaluated the elongation index, marker of erythrocyte deformability, the red blood cell distribution width (RDW), indicator of erythrocyte anisocytosis, hematocrit, hemoglobin and the main erythrocyte indices (MCV, MCH, MCHC) in basal conditions. Results: in comparison with a group of healthy not trained volunteers, the values of the elongation index, and not the RDW, are increased and this datum is accompanied by an increase of MCV and MCHC, likely related to an increased presence of circulating young erythrocytes in trained subjects. We also divided the same group according to the median of the VO2max, observing that the subgroup above the median shows both an increase in the elongation index values and a decrease in MCH and MCHC. Conclusions: in trained subjects there is no correlation between the values of elongation index and the RDW, while of particular interest and of a certain complexity seem the interrelations among elongation index, RDW and the main erythrocyte indices.

Keywords

regular exercise; red blood cell distribution width; erythrocyte indices; erythrocyte deformability; trained subjects.

Subject

Medicine and Pharmacology, Clinical Medicine

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