Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

National Burden and Trends for 29 Groups of Cancer in Mexico from 1990 to 2019: A Secondary Analysis of the Global Burden of Disease Study 2019

Version 1 : Received: 23 November 2023 / Approved: 23 November 2023 / Online: 23 November 2023 (14:05:52 CET)

A peer-reviewed article of this Preprint also exists.

Beltran-Ontiveros, S.A.; Contreras-Gutierrez, J.A.; Lizarraga-Verdugo, E.; Gutierrez-Grijalva, E.P.; Lopez-Lopez, K.; Lora-Fierro, E.H.; Trujillo-Rojas, M.A.; Moreno-Ortiz, J.M.; Cardoso-Angulo, D.L.; Leal-Leon, E.; Zatarain-Lopez, J.R.; Cuen-Diaz, H.M.; Montoya-Moreno, M.; Arce-Bojorquez, B.; Rochin-Teran, J.L.; Cuen-Lazcano, D.E.; Contreras-Rodriguez, V.A.; Lascurain, R.; Carmona-Aparicio, L.; Coballase-Urrutia, E.; Gallardo-Vera, F.; Diaz, D. National Burden and Trends for 29 Groups of Cancer in Mexico from 1990 to 2019: A Secondary Analysis of the Global Burden of Disease Study 2019. Cancers 2024, 16, 149. Beltran-Ontiveros, S.A.; Contreras-Gutierrez, J.A.; Lizarraga-Verdugo, E.; Gutierrez-Grijalva, E.P.; Lopez-Lopez, K.; Lora-Fierro, E.H.; Trujillo-Rojas, M.A.; Moreno-Ortiz, J.M.; Cardoso-Angulo, D.L.; Leal-Leon, E.; Zatarain-Lopez, J.R.; Cuen-Diaz, H.M.; Montoya-Moreno, M.; Arce-Bojorquez, B.; Rochin-Teran, J.L.; Cuen-Lazcano, D.E.; Contreras-Rodriguez, V.A.; Lascurain, R.; Carmona-Aparicio, L.; Coballase-Urrutia, E.; Gallardo-Vera, F.; Diaz, D. National Burden and Trends for 29 Groups of Cancer in Mexico from 1990 to 2019: A Secondary Analysis of the Global Burden of Disease Study 2019. Cancers 2024, 16, 149.

Abstract

The cancer burden is increasing worldwide with contrasting national patterns. Therefore, providing national estimations is necessary to understand and control this health issue. Herein, we comparatively describe incidence, mortality, and disability-adjusted lived years (DALYs) due to 29 groups of cancer in Mexico from 1990 to 2019 by sex and age. Using public data from the Global Burden of Disease Study 2019, we assessed the national burden of cancer using counts and crude and age-standardized rates per 100,000 people with 95% uncertainty intervals for 2019 and their trends using the annual percentage of change from 1990 to 2019. In 2019, cancer caused 222,060 incident cases, 105,591 deaths, and 2,86,054 DALYs in the general population. Nonmelanoma skin cancer, prostate cancer, and breast cancer had the highest incidence, and six groups of cancer (lung, colorectal, stomach, prostate, breast, and pancreatic) caused 53% of the deaths in 2019. From 1990 to 2019, incidence and mortality showed an increasing trend that varied between 10% and 436% among the groups of cancer, whereas the crude and age-standardized rates showed cancer-specific sex disparities. Our results demonstrate a substantial growth of the national burden of cancer with sex-specific patterns of change. These results may guide national efforts toward reducing health loss due to cancer.

Keywords

Burden of disease; Cancer epidemiology; Cancer mortality, Malignant neoplasm; Public health

Subject

Medicine and Pharmacology, Epidemiology and Infectious Diseases

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