Liu, D.; Yang, K.; Chen, S. Development and Future Trends of Protective Strategies for Magnesium Alloy Vascular Stents. Materials2024, 17, 68.
Liu, D.; Yang, K.; Chen, S. Development and Future Trends of Protective Strategies for Magnesium Alloy Vascular Stents. Materials 2024, 17, 68.
Liu, D.; Yang, K.; Chen, S. Development and Future Trends of Protective Strategies for Magnesium Alloy Vascular Stents. Materials2024, 17, 68.
Liu, D.; Yang, K.; Chen, S. Development and Future Trends of Protective Strategies for Magnesium Alloy Vascular Stents. Materials 2024, 17, 68.
Abstract
Magnesium alloy stents have been extensively studied in the field of biodegradable metal stents due to their exceptional biocompatibility, biodegradability and excellent biomechanical properties. Nevertheless, the specific in vivo service environment causes magnesium alloy stents to degrade rapidly and fail to provide sufficient support for certain time. This paper presents an overview of the development history and protection strategies for magnesium alloy stents. Alloying, optimizing stent structure and preparing protective coating have improved the corrosion resistance of magnesium alloy stents. Based on the corrosion mechanism of magnesium alloy stents, as well as their deformation during use and environmental characteristics, we present some novel solution strategies aiming at reducing the corrosion rate of magnesium alloys and enhancing the comprehensive performance of magnesium alloy stents. These strategies include adapting protective coatings for the deformation of the stents, preparing rapid endothelialization coatings to enhance the service environment of the stent, and constructing coatings with self-healing functions. It is hoped that this review can help to understand the development of magnesium alloy cardiovascular stents and solve the problems related to magnesium alloy stents in clinical applications at the early implantation stage.
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
