Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Pediatric Hemangiomas in the Female Genital Tract: A Comprehensive Analysis

Version 1 : Received: 13 November 2023 / Approved: 14 November 2023 / Online: 14 November 2023 (09:57:56 CET)

How to cite: Merlino, L.; Volpicelli, A.I.; Anglana, F.; D’Ovidio, G.; Dominoni, M.; Pasquali, M.F.; Gardella, B.; Inghirami, P.; Lippa, P.; Senatori, R. Pediatric Hemangiomas in the Female Genital Tract: A Comprehensive Analysis. Preprints 2023, 2023110898. https://doi.org/10.20944/preprints202311.0898.v1 Merlino, L.; Volpicelli, A.I.; Anglana, F.; D’Ovidio, G.; Dominoni, M.; Pasquali, M.F.; Gardella, B.; Inghirami, P.; Lippa, P.; Senatori, R. Pediatric Hemangiomas in the Female Genital Tract: A Comprehensive Analysis. Preprints 2023, 2023110898. https://doi.org/10.20944/preprints202311.0898.v1

Abstract

Background: Hemangiomas are an aberrant proliferation of blood vessels and are the most frequent benign pediatric soft tissue tumors. Despite their being common, genital localisation is rare. This study aimed to assist doctors in the diagnosis, management, and treatment of paediatric vulvovaginal hemangiomas by conducting a review of the literature and also gathering some cases of patients from our clinic.Methods: We conducted a literature review including papers published between October 2021 and April 2023, and we described the cases of 3 patients who referred to our clinic with vulvovaginal hemangioma.Results: While most of hemangiomas are usually indolent and resolve with time, in some cases, especially vaginal and cervical ones, they might present with severe symptoms like heavy bleeding and need further instrumental investigation for diagnosis, like CT or MRI. As for the treatment many options are available with medical therapy or expectant management being the first choice.Conclusions: Vulvovaginal pediatric hemangiomas are rare and, so, more research should be done to how to detect and manage this lesions, especially the symptomatic and the psychologically impacting ones. For the time being treatment should personalized based also on the patient situation and clinician’s expertise.

Keywords

pediatric hemangioma; vaginal hemangioma; vulvar hemangioma; hemangioma of low genital tract

Subject

Medicine and Pharmacology, Obstetrics and Gynaecology

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