Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Inflammation Indexes PLR, SII, AISI, MLR, and MCVL in Peripartum Treated Thrombophilia Peripartum Patients Undergoing Cesarean Section at Term

Catalina Filip
ORCID logo ,
Roxana Covali
* ORCID logo ,
Demetra Socolov
,
Ingrid Andrada Vasilache
ORCID logo ,
Alexandru Carauleanu
,
Mona Akad
* ,
Ioana Sadyie Scripcariu
,
Tudor Butureanu
ORCID logo ,
Ioana Pavaleanu
,
Gabriela Dumachita-Sargu
,
Lucian Vasile Boiculese
,
Alina Melinte
,
Razvan Socolov
ORCID logo
Version 1 : Received: 2 November 2023 / Approved: 3 November 2023 / Online: 3 November 2023 (05:05:21 CET)

How to cite: Filip, C.; Covali, R.; Socolov, D.; Vasilache, I.A.; Carauleanu, A.; Akad, M.; Scripcariu, I.S.; Butureanu, T.; Pavaleanu, I.; Dumachita-Sargu, G.; Boiculese, L.V.; Melinte, A.; Socolov, R. Inflammation Indexes PLR, SII, AISI, MLR, and MCVL in Peripartum Treated Thrombophilia Peripartum Patients Undergoing Cesarean Section at Term. Preprints 2023, 2023110209. https://doi.org/10.20944/preprints202311.0209.v1 Filip, C.; Covali, R.; Socolov, D.; Vasilache, I.A.; Carauleanu, A.; Akad, M.; Scripcariu, I.S.; Butureanu, T.; Pavaleanu, I.; Dumachita-Sargu, G.; Boiculese, L.V.; Melinte, A.; Socolov, R. Inflammation Indexes PLR, SII, AISI, MLR, and MCVL in Peripartum Treated Thrombophilia Peripartum Patients Undergoing Cesarean Section at Term. Preprints 2023, 2023110209. https://doi.org/10.20944/preprints202311.0209.v1

Abstract

(1) Background: Thrombophilia is a tendency towards hypercoagulability, and it is increased by pregnancy, and peaking around delivery.; (2) Methods: 80 Eighty thrombophilia patients admitted for delivery between 1/10/2017 and 1/12/2021 were prospectively studied, together with 80 eighty age- and para-matched control patients. Patients were admitted for delivery at term by means of cesarean section. The inflammation indexes from the complete blood count values analysis, in during both the 24 hours before and the 24 hours after labor—, extracted from the hospital’s medical records—, were calculated, and then correlated with uterine involution.; (3) Results: In pregnant patients treated for thrombophilia patients, the patients who did not manage to have close their uterine cavity closed with in the first 24-48 hours had significantly higher SII and AISI inflammation indexes SII and AISI , than the onesthose who did manage to have their uterine cavity closed their uterine cavity. In pregnant patients treated for thrombophilia patients, MLR is higher in patients without the Rh factor than in those with the Rh factor. In non-thrombophilia patients, PLR was significantly higher as compared to treated thrombophilia patients. In non-thrombophilia patients, MCVL increased with age and, before labor, while SII and AISI increased with age, postpartum. ; (4) Conclusions: There may be an underlying inflammation state that persisted despite treatment in some pregnant thrombophilia pregnant patients.

Keywords

thrombophilia; pregnancy; postpartum uterine ultrasonographic scale; SII; AISI; MLR; PLR; MCVL; Rh factor; age.

Subject

Medicine and Pharmacology, Obstetrics and Gynaecology

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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