Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

mRNA Vaccines: A Prospective Analysis of Long-term, Multi-target, and Autoimmune Disorders

Version 1 : Received: 30 October 2023 / Approved: 31 October 2023 / Online: 31 October 2023 (05:11:07 CET)

How to cite: Niazi, S.K. mRNA Vaccines: A Prospective Analysis of Long-term, Multi-target, and Autoimmune Disorders. Preprints 2023, 2023101981. https://doi.org/10.20944/preprints202310.1981.v1 Niazi, S.K. mRNA Vaccines: A Prospective Analysis of Long-term, Multi-target, and Autoimmune Disorders. Preprints 2023, 2023101981. https://doi.org/10.20944/preprints202310.1981.v1

Abstract

The new class of mRNA vaccines is studied extensively, leading to many novel prospects based on the pivotal success of vaccines against the SARS-Cov-2 virus. Many novel mechanisms of immune response discovered have led to the possibility of mutation-resistant vaccines by combining multiple conserved epitopes as antigens to manipulate the T-cell and B-cell responses; these antigens can also come from different organisms, providing protection against numerous diseases and of most tremendous significance is the utility of mRNA vaccines in preventing and treating more than 100 autoimmune disorders. This is a significant humanitarian breakthrough given the ease and faster and low cost of mRNA vaccines, being a chemical entity. This paper provides a prospective analysis of mRNA vaccines with much broader applications than anticipated when these vaccines entered treating SARS-Cov-2 infections.

Keywords

T-cell-mediated immunity; vaccines; infectious diseases; viral vectors; mRNA vaccines

Subject

Medicine and Pharmacology, Pharmacology and Toxicology

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