preprints.org > biology and life sciences > animal science, veterinary science and zoology > doi: 10.20944/preprints202310.1977.v1

Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Version 1 : Received: 30 October 2023 / Approved: 31 October 2023 / Online: 31 October 2023 (05:08:45 CET)

Authors evaluated the relevant literature related to the purging which is the interaction between selection and inbreeding where the population may get rid of its inbreeding load at least partially. The backroad of the relevant theory was given and the available methods were described both based on the conventional quantitative genetic approach (based on genealogy data) and based on the latest genomic methods. The different parameters necessary for signalling purging (highlighting those inbreeding coefficients which are not yet been widely known in animal and veterinary science) were presented together with the relevant results of the literature. The available statistical methods together with the softwares and R packages to calculate various inbreeding coefficients and to determine inbreeding depression and purging were provided. The main results of the different approaches obtained in laboratory ZOO and domesticated populations (lethal equivalents, ancestral inbreeding, Inbreeding-Purging Model, genomic approaches) were summarized and presented. Application possibilities and future prospective of purging was also discussed.

purging; lethal equivalent, ancestral inbreeding; old inbreeding, new inbreeding, Inbreeding-Purging Model, purging coefficient, purged inbreeding coefficient

Biology and Life Sciences, Animal Science, Veterinary Science and Zoology

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