Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Enhanced Precision and Safety in Thermal Ablation: O-arm CBCT-MRI Fusion for Spinal Column Tumor Targeting

Version 1 : Received: 26 October 2023 / Approved: 26 October 2023 / Online: 26 October 2023 (11:35:31 CEST)

A peer-reviewed article of this Preprint also exists.

Aslan, S.; Al-Smadi, M.W.; Kozma, I.; Viola, Á. Enhanced Precision and Safety in Thermal Ablation: O-Arm Cone Beam Computed Tomography with Magnetic Resonance Imaging Fusion for Spinal Column Tumor Targeting. Cancers 2023, 15, 5744. Aslan, S.; Al-Smadi, M.W.; Kozma, I.; Viola, Á. Enhanced Precision and Safety in Thermal Ablation: O-Arm Cone Beam Computed Tomography with Magnetic Resonance Imaging Fusion for Spinal Column Tumor Targeting. Cancers 2023, 15, 5744.

Abstract

Spinal metastatic tumors are common and often cause debilitating symptoms. Image-guided percutaneous thermal ablation (IPTA) has gained significant recognition in managing spinal column tumors due to its exceptional precision and effectiveness. Conventional guidance modalities, including computed tomography, fluoroscopy, and ultrasound, have been important in targeting spinal column tumors while minimizing harm to adjacent critical structures. This study presents a novel approach utilizing a fusion of Cone Beam Computed Tomography with Magnetic Resonance Imaging to guide percutaneous thermal ablation for four patients with secondary spinal column tumors. The visual analog scale (VAS) evaluated procedure effectiveness during an 18-month follow-up. Percutaneous vertebroplasty was performed in two cases, and a thermostat was used during all procedures. Imaging was performed using the Stealth Station navigation system Spine 8 (SSS8) and a 1.5T MRI machine. The fusion of CBCT with MRI allowed precise tumor localization and guidance for thermal ablation. Initial results indicate successful tumor ablation and symptom reduction, emphasizing the potential of CBCT-MRI fusion in spinal column tumor management. This innovative approach is promising in optimizing therapy for secondary spinal column tumors. Further studies are necessary to validate its efficacy and applicability.

Keywords

percutaneous thermal ablation; image-guided procedures; Cone Beam Computed Tomography (CBCT); fusion imaging; thermal ablation techniques; secondary spinal tumors; interventional radiology

Subject

Medicine and Pharmacology, Oncology and Oncogenics

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