Colorectal Cancer: Current Updates and Future Perspectives

Rosa Marcellinaro; Domenico Spoletini; Michele Grieco; Pasquale Avella; Micaela Cappuccio; Raffaele Troiano; Giorgio Lisi; Giovanni M. Garbarino; Massimo Carlini

doi:10.20944/preprints202310.1321.v1

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preprints.org > medicine and pharmacology > surgery > doi: 10.20944/preprints202310.1321.v1

Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Colorectal Cancer: Current Updates and Future Perspectives

^* ,

Giovanni M. Garbarino

Massimo Carlini

Version 1 : Received: 19 October 2023 / Approved: 20 October 2023 / Online: 20 October 2023 (08:31:13 CEST)

A peer-reviewed article of this Preprint also exists.

Marcellinaro, R.; Spoletini, D.; Grieco, M.; Avella, P.; Cappuccio, M.; Troiano, R.; Lisi, G.; Garbarino, G.M.; Carlini, M. Colorectal Cancer: Current Updates and Future Perspectives. J. Clin. Med. 2024, 13, 40. Marcellinaro, R.; Spoletini, D.; Grieco, M.; Avella, P.; Cappuccio, M.; Troiano, R.; Lisi, G.; Garbarino, G.M.; Carlini, M. Colorectal Cancer: Current Updates and Future Perspectives. J. Clin. Med. 2024, 13, 40.

Abstract

Colorectal cancer is a frequent neoplasm in western countries, mainly due to dietary and behavioral factors. Its incidence is growing in developing countries for the westernization of foods and lifestyles. An increased incidence rate is observed in patients under 45 years of age. In last years the mortality for CRC is decreased, but this trend is slowing. The mortality rate is reducing in those countries where prevention and treatments have been implemented. The survival is increased to over 65%. This trend reflects earlier detection of CRC through routine clinical examinations and screening, more accurate staging through advances in imaging, improvements in surgical techniques and advances in chemotherapy and radiation. The most important predictor of survival is the stage at diagnosis. The screening programs are able to reduce incidence and mortality rates of CRC. The aim of this paper is to provide a comprehensive overview of incidence, mortality and survival rate for CRC.

Keywords

colorectal cancer; incidence; mortality; screening; survival

Subject

Medicine and Pharmacology, Surgery

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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