Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Atomic Layer Deposition of Antibacterial Nanocoatings: A Review

Version 1 : Received: 18 October 2023 / Approved: 19 October 2023 / Online: 19 October 2023 (11:35:28 CEST)

A peer-reviewed article of this Preprint also exists.

Nazarov, D.; Kozlova, L.; Rogacheva, E.; Kraeva, L.; Maximov, M. Atomic Layer Deposition of Antibacterial Nanocoatings: A Review. Antibiotics 2023, 12, 1656. Nazarov, D.; Kozlova, L.; Rogacheva, E.; Kraeva, L.; Maximov, M. Atomic Layer Deposition of Antibacterial Nanocoatings: A Review. Antibiotics 2023, 12, 1656.

Abstract

In recent years, antibacterial coatings have become a significant approach in the global fight against bacterial pathogens. Developments in materials science, chemistry and biochemistry have led to a plethora of materials and chemical compounds that have potential for creating antibacterial coatings. Nonetheless, there has been insufficient consideration given to the analysis of the techniques and technologies used to apply these coatings. Among the various inorganic coating techniques, Atomic Layer Deposition (ALD) is noteworthy. It enables the successful synthesis of high-purity inorganic nanocoatings on surfaces of complex shape and topography, while also providing precise control over their thickness and composition. ALD has various industrial applications, but its practical application in medicine is still limited. In recent years, a substantial number of papers have been published on the suggested implementation of thin films and coatings produced through ALD in medicine, notably those with antibacterial properties. The aim of this paper is to carefully evaluate and analyse the relevant literature on this subject. Simple oxide coatings, including TiO2, ZnO, Fe2O3, MgO, and ZrO2, were examined, as well as coatings containing metal nanoparticles such as Ag, Cu, Pt, and Au, and mixed systems such as TiO2-ZnO, TiO2-ZrO2, ZnO-Al2O3, TiO2-Ag, and ZnO-Ag. Through comparative analysis, we have been able to draw conclusions on the effectiveness of various antibacterial coatings of different compositions, including key characteristics such as thickness, morphology, and crystal structure. ALD has been analysed in its use for developing antibacterial coatings for various applications. Furthermore, assumptions regarding the most promising development areas have been presented.

Keywords

Atomic layer deposition; antibacterial coatings; zinc oxide; titanium oxide; silver coatings; medical implants

Subject

Chemistry and Materials Science, Surfaces, Coatings and Films

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