Version 1
: Received: 16 October 2023 / Approved: 19 October 2023 / Online: 19 October 2023 (05:37:21 CEST)
How to cite:
Mei, E.; Hai, B.; Xiang, K. Inflammatory Markers for the Development of Obliterative Bronchiolitis after Adenovirus Infection in Children. Preprints2023, 2023101226. https://doi.org/10.20944/preprints202310.1226.v1
Mei, E.; Hai, B.; Xiang, K. Inflammatory Markers for the Development of Obliterative Bronchiolitis after Adenovirus Infection in Children. Preprints 2023, 2023101226. https://doi.org/10.20944/preprints202310.1226.v1
Mei, E.; Hai, B.; Xiang, K. Inflammatory Markers for the Development of Obliterative Bronchiolitis after Adenovirus Infection in Children. Preprints2023, 2023101226. https://doi.org/10.20944/preprints202310.1226.v1
APA Style
Mei, E., Hai, B., & Xiang, K. (2023). Inflammatory Markers for the Development of Obliterative Bronchiolitis after Adenovirus Infection in Children. Preprints. https://doi.org/10.20944/preprints202310.1226.v1
Chicago/Turabian Style
Mei, E., Bengang Hai and Keke Xiang. 2023 "Inflammatory Markers for the Development of Obliterative Bronchiolitis after Adenovirus Infection in Children" Preprints. https://doi.org/10.20944/preprints202310.1226.v1
Abstract
Objective: To explore the inflammatory markers for the development of obliterative bronchiolitis (OB) after adenovirus infection in children. Methods: In this retrospective study, the medical data of 62 children with adenovirus pneumonia treated in our hospital between February 2020 and November 2021 were collected and assigned to an OB group (n = 30) or non-OB group (n = 32) according to the presence of OB. Clinical characteristics of patients included gender, age, prematurity, underlying disease, length of hospitalization, type of adenovirus infection, ventilator use, length of ventilator use, and laboratory index levels. Results: Children with OB were associated with higher serum ferritin levels versus those without (P < 0.05). There were no significant differences in the immunoglobulin E (IgE), interleukin-6 (IL-6), partial arterial pressure of oxygen (PaO2), D-dimer, lactate dehydrogenase (LDH), and lymphocyte absolute values between the two groups of children (P > 0.05). Logistic multifactorial regression analysis revealed that the length of ventilator use and serum ferritin level were inflammatory markers for the development of OB in children with adenovirus pneumonia. Conclusion: The length of ventilator use and serum ferritin levels are inflammatory markers for the development of OB after adenovirus infection in children, and timely measurement of the above indicators in children is instrumental in predicting the prognosis of children.
Medicine and Pharmacology, Pediatrics, Perinatology and Child Health
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
