Version 1
: Received: 16 October 2023 / Approved: 16 October 2023 / Online: 16 October 2023 (15:42:17 CEST)
How to cite:
Luo, F.; Zhang, L.; Cao, H.; Wen, R.; Shang, W.; Cheng, X. Clinical Efficacy of Antibiotic Bone Cement plus Lateral Bone Repositioning for Severe Diabetic Foot and Its Impact on Wound Healing Rate. Preprints2023, 2023100965. https://doi.org/10.20944/preprints202310.0965.v1
Luo, F.; Zhang, L.; Cao, H.; Wen, R.; Shang, W.; Cheng, X. Clinical Efficacy of Antibiotic Bone Cement plus Lateral Bone Repositioning for Severe Diabetic Foot and Its Impact on Wound Healing Rate. Preprints 2023, 2023100965. https://doi.org/10.20944/preprints202310.0965.v1
Luo, F.; Zhang, L.; Cao, H.; Wen, R.; Shang, W.; Cheng, X. Clinical Efficacy of Antibiotic Bone Cement plus Lateral Bone Repositioning for Severe Diabetic Foot and Its Impact on Wound Healing Rate. Preprints2023, 2023100965. https://doi.org/10.20944/preprints202310.0965.v1
APA Style
Luo, F., Zhang, L., Cao, H., Wen, R., Shang, W., & Cheng, X. (2023). Clinical Efficacy of Antibiotic Bone Cement plus Lateral Bone Repositioning for Severe Diabetic Foot and Its Impact on Wound Healing Rate. Preprints. https://doi.org/10.20944/preprints202310.0965.v1
Chicago/Turabian Style
Luo, F., Wei Shang and Xinhua Cheng. 2023 "Clinical Efficacy of Antibiotic Bone Cement plus Lateral Bone Repositioning for Severe Diabetic Foot and Its Impact on Wound Healing Rate" Preprints. https://doi.org/10.20944/preprints202310.0965.v1
Abstract
Objective: To evaluate the clinical efficacy of antibiotic bone cement plus lateral bone repositioning for severe diabetic foot and its impact on wound healing rate. Methods: Sixty patients with hemodialysis anemia admitted to the endocrinology department of our hospital from July 2020 to July 2021 were included and randomly assigned to receive antibiotic bone cement plus lateral bone repositioning (observation group) or vacuum sealing drainage (VSD) (control group). Outcome measures included skin temperature of the affected limb, ankle-brachial index, sensory threshold, foot wound healing, dorsalis pedis artery hemodynamics, lower limb function and clinical efficacy. Results: Antibiotic bone cement plus lateral bone repositioning resulted in significantly higher treatment efficiency and transcutaneous partial pressure of oxygen, smaller wound, and lower trauma pH versus VSD, suggesting that antibiotic bone cement plus lateral bone repositioning contributes to potentiating the treatment efficacy and reducing the foot ulcer trauma, thereby facilitating rapid recovery. Patients given antibiotic bone cement plus lateral bone repositioning had larger vascular internal diameter and blood flow and better sensory conduction velocity of the common peroneal nerve and the motor conduction velocity of the tibial nerve versus those given VSD, indicating its vascular and neurological benefits. Conclusion: Antibiotic bone cement plus lateral bone repositioning enhances the treatment efficiency, boosts trauma healing, and promotes postoperative functional recovery of patients.
Keywords
Diabetic foot; Severe disease; Antibiotic bone cement; Lateral bone repositioning; Lower limb function; Dorsalis pedis artery hemodynamics
Subject
Medicine and Pharmacology, Orthopedics and Sports Medicine
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
