Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Biofilm-Associated Proteins as Potential Drug Targets

Version 1 : Received: 8 October 2023 / Approved: 13 October 2023 / Online: 13 October 2023 (11:34:33 CEST)

How to cite: Nor, H.; Mohd, Z. Biofilm-Associated Proteins as Potential Drug Targets. Preprints 2023, 2023100881. https://doi.org/10.20944/preprints202310.0881.v1 Nor, H.; Mohd, Z. Biofilm-Associated Proteins as Potential Drug Targets. Preprints 2023, 2023100881. https://doi.org/10.20944/preprints202310.0881.v1

Abstract

Biofilm-associated proteins (BAPs) are important in the development and resilience of biofilms, which are intricate populations of microbes protected by extracellular matrix. All members of the BAP family are known to possess common characteristics such as high molecular weight and a signal sequence for extracellular secretion. It has been shown that BAPs are directly linked to the pathogenicity of many bacteria. This mini review highlights several potential strategies to target BAPs for drug development.

Keywords

Biofilm; proteins; drug target; essential; non-host homologous

Subject

Biology and Life Sciences, Immunology and Microbiology

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