Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Using Ziziphora serpyllacea Leaf Extract to Detoxify Aflatoxin B1 from Various Nuts

Version 1 : Received: 11 October 2023 / Approved: 12 October 2023 / Online: 13 October 2023 (08:12:23 CEST)

How to cite: Auteleyeva, L.; Maikanov, B.; Sharipbaeva, A.; Smagulova, A. Using Ziziphora serpyllacea Leaf Extract to Detoxify Aflatoxin B1 from Various Nuts. Preprints 2023, 2023100858. https://doi.org/10.20944/preprints202310.0858.v1 Auteleyeva, L.; Maikanov, B.; Sharipbaeva, A.; Smagulova, A. Using Ziziphora serpyllacea Leaf Extract to Detoxify Aflatoxin B1 from Various Nuts. Preprints 2023, 2023100858. https://doi.org/10.20944/preprints202310.0858.v1

Abstract

The class I carcinogen aflatoxin B1 (AFB1) poses a significant risk to human health. The contamination of food sources contributes to the spread of AFB1, mainly through grains and nuts, from Aspergillus flavus. The high percentage of aflatoxin contamination in various imported nuts in the Republic of Kazakhstan has encouraged researchers to develop a local method of AFB1 detoxification. This research was focused on studying the ability of Ziziphora serpyllace leaf extract growing in the Akmola region of the Republic of Kazakhstan to inactivate aflatoxin B1 in various nuts. For the first time, an extract of Ziziphora serpyllace leaves growing in the territory of the Republic of Kazakhstan was used to detoxify AFB1 in nuts, and this demonstrated low cytotoxic activity, high antimicrobial and high antifungal activity, while preserving the qualitative characteristics of the nuts.

Keywords

various nuts; mycotoxins; aflatoxin B1; detoxification; Ziziphora serpyllacea

Subject

Biology and Life Sciences, Food Science and Technology

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