Preprint Case Report Version 2 Preserved in Portico This version is not peer-reviewed

A Brief Case Report on Umbilical Cord Connective Tissue Allograft Application for Defects of the Achilles Tendon

Version 1 : Received: 5 October 2023 / Approved: 6 October 2023 / Online: 6 October 2023 (16:21:56 CEST)
Version 2 : Received: 13 November 2023 / Approved: 14 November 2023 / Online: 14 November 2023 (15:45:50 CET)

How to cite: Parker, R.; Shou, J.; Lambert, N.; Woods, C.; Barrett, A.T. A Brief Case Report on Umbilical Cord Connective Tissue Allograft Application for Defects of the Achilles Tendon. Preprints 2023, 2023100360. https://doi.org/10.20944/preprints202310.0360.v2 Parker, R.; Shou, J.; Lambert, N.; Woods, C.; Barrett, A.T. A Brief Case Report on Umbilical Cord Connective Tissue Allograft Application for Defects of the Achilles Tendon. Preprints 2023, 2023100360. https://doi.org/10.20944/preprints202310.0360.v2

Abstract

Damaged connective tissues between the bone and tendons or ligaments are common among adults regardless of activity level. Achilles tendinosis is one of the most common tissue defects and enthesopathies. The patient in this study is a 54-year-old female with chronic Achilles tendinosis from chronic enthesopathy at the Achilles tendon insertion with a retrocalcaneal exostosis for three years who has failed standard-of-care practices for over two years. The patient received extracorporeal pulsed-activated therapy (EPAT) before applying 2ml of CryoText, a Wharton’s jelly tissue allograft. The patient then received class IV laser therapy treatments twice weekly for three weeks. The patient started with a 10/10 VAS at the initial visit. At five weeks post-application, the patient’s score had improved by 80% at 2/10 VAS. By week 13, the patient rated her pain as 0/10 VAS. The improvement in patient-reported pain and functionality reported in this study after the application of Wharton’s Jelly, EPAT, and class IV laser therapy warrants future research studying the safety and efficacy of these patient care modalities together.

Keywords

Achilles tendinosis; Enthesopathies; Wharton’s Jelly; laser therapy; EPAT; Regenerative Medicine

Subject

Medicine and Pharmacology, Complementary and Alternative Medicine

Comments (1)

Comment 1
Received: 14 November 2023
Commenter: Naomi Lambert
Commenter's Conflict of Interests: Author
Comment: This updated version contains edits suggested by the reviewers from MDPIs Reports journal.
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