Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

How Thyroid Surgery Has Changed in the Last 25 Years?

Version 1 : Received: 5 October 2023 / Approved: 6 October 2023 / Online: 6 October 2023 (11:30:08 CEST)

How to cite: Wojtczak, B.; Sępek, M.; Sutkowski, K.; Marciniak, D.M.; Kaliszewski, K. How Thyroid Surgery Has Changed in the Last 25 Years?. Preprints 2023, 2023100333. https://doi.org/10.20944/preprints202310.0333.v1 Wojtczak, B.; Sępek, M.; Sutkowski, K.; Marciniak, D.M.; Kaliszewski, K. How Thyroid Surgery Has Changed in the Last 25 Years?. Preprints 2023, 2023100333. https://doi.org/10.20944/preprints202310.0333.v1

Abstract

Thyroid surgery has been for years one of the most common elective procedures performed in general surgery. In the last 25 years, there have been significant advances in the diagnosis and treatment of thyroid disorders, and new technologies are being implemented. The aim of this study was to ana-lyze 25 years of experience in thyroid surgery in the Department of General, Minimally Invasive and Endocrine Surgery at the Medical University of Wroclaw in terms of demographic changes, indica-tions for surgical treatment, the type of thyroid surgery performed and complications. The impact of recent advances on changes in endocrine surgery was evaluated. For this purpose, clinical material from the years 1996-2020 was analyzed, with a total of 3748 patients (7285 RLN at risk of injury). Period I included the years: 1996-2003, period II: 2011-2015 and 2018-2020. Results: In the last 25 years, the percentage of patients operated on for thyroid cancer has increased threefold (p <0.00001); the extent of thyroid surgery has changed: in 1996-2003, subtotal thyroid operation was performed in more than 90% of patients vs. 1.7% of total thyroid gland surgery; 2011-2015 and 2018-2020 were more than 94% of total thyroid surgery vs. 4% of subtotal surgery (p<0.00001). The increase in the extent of surgery did not affect the percentage of total amount recurrent laryngeal nerve palsy (RLN palsy) (5.17% vs. 4.38% p = 0.1785), it did affect the percentage of transient RLN palsy in group II vs. group I (0.41% vs. 1.34%, p<0.00001), while the percentage of permanent RLN palsy in group I was statistically significantly higher than in group II (4.77% vs. 3.05%, p=0.0016). An increase in the percentage of postoperative clinical hypoparathyroidism in group II was observed: 4.84% vs. 8.93% (p<0.00001). Conclusions: Over 25 years, there has been a significant increase in the number of sur-geries performed for thyroid cancer, the range of surgeries from partial resections to total excision of the thyroid gland has changed, and the increased range of surgeries did not have a statistically signifi-cant effect on the number of vocal fold paralysis, but increased the percentage of postoperative hypo-parathyroidism. Intraoperative neuromonitoring had a significant impact on changing the scope of surgery and preventing complications.

Keywords

thyroidectomy, complications, recurrent laryngeal nerve, hypoparathyroidism, thyroid cancer, neuromonitoring

Subject

Medicine and Pharmacology, Surgery

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