Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Cannabis and Endometriosis: The Roles of the Gut Microbiota and the Endocannabinoid System

Version 1 : Received: 4 October 2023 / Approved: 4 October 2023 / Online: 4 October 2023 (10:52:24 CEST)
Version 2 : Received: 4 October 2023 / Approved: 6 October 2023 / Online: 9 October 2023 (15:10:17 CEST)

A peer-reviewed article of this Preprint also exists.

Farooqi, T.; Bhuyan, D.J.; Low, M.; Sinclair, J.; Leonardi, M.; Armour, M. Cannabis and Endometriosis: The Roles of the Gut Microbiota and the Endocannabinoid System. J. Clin. Med. 2023, 12, 7071. Farooqi, T.; Bhuyan, D.J.; Low, M.; Sinclair, J.; Leonardi, M.; Armour, M. Cannabis and Endometriosis: The Roles of the Gut Microbiota and the Endocannabinoid System. J. Clin. Med. 2023, 12, 7071.

Abstract

There is a growing interest in the endocannabinoid system and the gut microbiota. Both areas have been suggested to play a role in endometriosis, however this is yet to be studied comprehensively. The purpose of this narrative review is to identify the gaps in endometriosis research in the context of these two areas. It underscores the limited knowledge regarding the involvement of the endocannabinoid system and gut microbiota in endometriosis. Further research in these areas is essential to unlock the therapeutic potential of cannabis and enhance the understanding of endometriosis pathogenesis.

Keywords

endometriosis; the endocannabinoid system; CB1; CB2; gut microbiota

Subject

Medicine and Pharmacology, Clinical Medicine

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