Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

The Impact of Moderate Alcohol Consumption Combined with Physical Activity on Post-Acute Myocardial Infarction Survival and Recovery

Version 1 : Received: 2 October 2023 / Approved: 3 October 2023 / Online: 3 October 2023 (11:16:52 CEST)

How to cite: Rus, M.; Ardelean, A.I.; Crisan, S.; Luca, C.T.; Marian, P.; Pobirci, O.L.; Pobirci, D.D.; Huplea, V.; Osiceanu, A.S.; Osiceanu, A.G.; Staniș, C.E.; Andronie-Cioara, F.L. The Impact of Moderate Alcohol Consumption Combined with Physical Activity on Post-Acute Myocardial Infarction Survival and Recovery. Preprints 2023, 2023100146. https://doi.org/10.20944/preprints202310.0146.v1 Rus, M.; Ardelean, A.I.; Crisan, S.; Luca, C.T.; Marian, P.; Pobirci, O.L.; Pobirci, D.D.; Huplea, V.; Osiceanu, A.S.; Osiceanu, A.G.; Staniș, C.E.; Andronie-Cioara, F.L. The Impact of Moderate Alcohol Consumption Combined with Physical Activity on Post-Acute Myocardial Infarction Survival and Recovery. Preprints 2023, 2023100146. https://doi.org/10.20944/preprints202310.0146.v1

Abstract

Objective: The objective of our study was to explore the potential benefits of combining moderate alcohol consumption with regular vigorous physical activity on HDL-cholesterol levels and its potential positive impact on cardiovascular health. Material and method: The study comprised two groups: group A (102 patients) who consumed 1 gram of alcohol per day, specifically red wine, and increased their exercise levels in addition to their standard medical treatment, and group B (108 patients) who adhered only to their standard medical treatment. The patients were monitored for a year, during which various clinical parameters were observed. Results:Our study showed that moderate alcohol consumption, particularly red wine, along with increased physical activity levels, was associated with enhancements in exercise tolerance and elevated levels of HDL-cholesterol. Our findings suggest the efficacy of the intervention in improving lipid profiles, with the group that consumed alcohol as part of their treatment scheme, generally experiencing more pronounced positive effects. Statistically significant differences between groups in terms of angina evolution, AMI recurrence, or arrhythmias evolution were not found. However, there were important differences in terms of EF improvement and quality of life, with the alcohol consuming group displaying greater improvements in both aspects. Conclusions:In conclusion, our study emphasizes the potential benefits of combining moderate alcohol consumption, specifically red wine, with increased physical activity levels for improving exercise tolerance and enhancing HDL-cholesterol levels. However, further research and clinical trials are essential to fully understand the mechanisms and optimize the integration of these lifestyle elements for improved cardiovascular health outcomes.

Keywords

moderate alcohol consumption; physical activity; HDL-cholesterol; exercise tolerance; atherosclerotic plaques; quality of life; cardiovascular health

Subject

Medicine and Pharmacology, Cardiac and Cardiovascular Systems

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