Version 1
: Received: 26 September 2023 / Approved: 26 September 2023 / Online: 27 September 2023 (02:52:18 CEST)
Version 2
: Received: 27 September 2023 / Approved: 13 October 2023 / Online: 18 October 2023 (04:23:27 CEST)
Elmas, H.; Önal, B.; Steurer, S.; Hantzsch-Kuhn, B.; Claussen, M.; Mehdi, E.; Ince, Ü.; Rabe, K.F.; Sauter, G.; Welker, L. Rapid Remote Online Evaluation in Endoscopic Diagnostics: An Analysis of Biopsy-Proven Respiratory Cytopathology. Diagnostics2023, 13, 3329.
Elmas, H.; Önal, B.; Steurer, S.; Hantzsch-Kuhn, B.; Claussen, M.; Mehdi, E.; Ince, Ü.; Rabe, K.F.; Sauter, G.; Welker, L. Rapid Remote Online Evaluation in Endoscopic Diagnostics: An Analysis of Biopsy-Proven Respiratory Cytopathology. Diagnostics 2023, 13, 3329.
Elmas, H.; Önal, B.; Steurer, S.; Hantzsch-Kuhn, B.; Claussen, M.; Mehdi, E.; Ince, Ü.; Rabe, K.F.; Sauter, G.; Welker, L. Rapid Remote Online Evaluation in Endoscopic Diagnostics: An Analysis of Biopsy-Proven Respiratory Cytopathology. Diagnostics2023, 13, 3329.
Elmas, H.; Önal, B.; Steurer, S.; Hantzsch-Kuhn, B.; Claussen, M.; Mehdi, E.; Ince, Ü.; Rabe, K.F.; Sauter, G.; Welker, L. Rapid Remote Online Evaluation in Endoscopic Diagnostics: An Analysis of Biopsy-Proven Respiratory Cytopathology. Diagnostics 2023, 13, 3329.
Abstract
Background: This prospective study assesses the use of Rapid Remote Online Cytological Evaluation analysis for diagnosing endoscopical achieved biopsies. It focuses on its effectiveness in identifying benign and malignant conditions using digital image processing. Methods: The study was conducted between April 2021 and September 2022 and involved a total of 314 Rapid Remote Online Cytological Evaluations (17 brush, 143 fine needle aspirations and 154 imprint cytologies) analyses performed on 239 patients at the LungenClinic Grosshansdorf. During on-site evaluation via telecytology, the time requirement was determined and the findings were compared with the cyto-/histological and final diagnoses. Results: By means of Rapid Remote Online Evaluation, 86 cytological benign and 190 malignant and 38 findings of unclear diagnosis were recorded (Ø assessment time 100 sec., range 11 - 370sec.). In 27 of the 38 cases with unclear diagnosis, the final findings were malignant tumours and only 6 were benign changes. The diagnosis of another five of these 38 cases remained unclear. Excluding these 38 findings, the Rapid Remote online cytology achieved a sensitivity of 78.6% with a specificity of 99.5% and a correct classification rate of 93.1% with regard to the final diagnosis of all cases. As expected, an increase in the sensitivity rate for the cytological detection of malignant tumours (76.1% vs. 92.5%) was found especially in fine-needle aspirations. Conclusions: Rapid remote online analysis allows fast quantitative and qualitative evaluation of clinically obtained cytological specimens. With a correct classification rate of more than 93%, sampling deficiencies can be corrected promptly and diagnostic and therapeutic approaches can be derived.
Medicine and Pharmacology, Pathology and Pathobiology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Received:
18 October 2023
Commenter:
Hatice Elmas
Commenter's Conflict of Interests:
Author
Comment:
The Rapid Remote Online Evaluation allows rapid quantitative and qualitative evaluation of clinically obtained cytological specimens. With a correct classification rate of more than 93%, biopsy deficiencies can be corrected promptly and diagnostic and therapeutic decisions can be derived—quantitative and qualitative evaluation of clinically obtained cytological specimens. With a correct classification rate of more than 93%, biopsy deficiencies can be corrected promptly and diagnostic and therapeutic decisions can be derived.
Commenter: Hatice Elmas
Commenter's Conflict of Interests: Author