Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Evolution and Current Status of Influenza A Virus in Chile: A Review

Version 1 : Received: 17 September 2023 / Approved: 18 September 2023 / Online: 19 September 2023 (03:54:36 CEST)

A peer-reviewed article of this Preprint also exists.

Godoy, M.; Oca, M.M.; Caro, D.; Pontigo, J.P.; Kibenge, M.; Kibenge, F. Evolution and Current Status of Influenza A Virus in Chile: A Review. Pathogens 2023, 12, 1252. Godoy, M.; Oca, M.M.; Caro, D.; Pontigo, J.P.; Kibenge, M.; Kibenge, F. Evolution and Current Status of Influenza A Virus in Chile: A Review. Pathogens 2023, 12, 1252.

Abstract

The Influenza A virus (IAV) is a highly infectious virus that poses a significant threat to global public health and food supplies. The current subtype of avian influenza virus (AIV), H5N1, is being closely monitored worldwide due to its unprecedented spread from Europe to North America and now to Central and South America. This review summarizes recent updates on the evolution of the different IAV subtypes in birds and mammals including humans, in Chile. The distribution and spread of AIV H5N1 in Chile indicated a complex interplay between ecological and human factors in that it was negatively correlated with distance to the closest urban center and precipitation and temperature seasonality. It is evident that highly pathogenic avian influenza (HPAI) H5N1 in Chile was introduced from North America via the Atlantic migratory flyways as opposed to local transmission from other countries in South America. The presence of these viruses in Chile underscores the need for increased biosecurity on poultry farms and continuous genomic surveillance approaches to understand and control AIVs in both wild and domestic bird populations in Chile.

Keywords

Influenza A virus; avian influenza virus; genomic surveillance; poultry farms; wild birds; HPAI H5N1.

Subject

Biology and Life Sciences, Virology

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