Version 1
: Received: 6 September 2023 / Approved: 11 September 2023 / Online: 12 September 2023 (16:46:00 CEST)
How to cite:
Ljubisavljevic, S.; Damjanovic, R.; Ljubisavljevic, M.; Kalinic, S. A Descriptive Review of Medication Overuse HEADACHE-from Pathophysiology to the Clinic. Preprints2023, 2023090760. https://doi.org/10.20944/preprints202309.0760.v1
Ljubisavljevic, S.; Damjanovic, R.; Ljubisavljevic, M.; Kalinic, S. A Descriptive Review of Medication Overuse HEADACHE-from Pathophysiology to the Clinic. Preprints 2023, 2023090760. https://doi.org/10.20944/preprints202309.0760.v1
Ljubisavljevic, S.; Damjanovic, R.; Ljubisavljevic, M.; Kalinic, S. A Descriptive Review of Medication Overuse HEADACHE-from Pathophysiology to the Clinic. Preprints2023, 2023090760. https://doi.org/10.20944/preprints202309.0760.v1
APA Style
Ljubisavljevic, S., Damjanovic, R., Ljubisavljevic, M., & Kalinic, S. (2023). A Descriptive Review of Medication Overuse HEADACHE-from Pathophysiology to the Clinic. Preprints. https://doi.org/10.20944/preprints202309.0760.v1
Chicago/Turabian Style
Ljubisavljevic, S., Marina Ljubisavljevic and Sreten Kalinic. 2023 "A Descriptive Review of Medication Overuse HEADACHE-from Pathophysiology to the Clinic" Preprints. https://doi.org/10.20944/preprints202309.0760.v1
Abstract
Purpose of review: Medication overuse headache (MOH) is an important problem worlwide areas of different controversy regarding its entity. This article reviews the risk factors, comorbidities, pathophysiology, clinical presentation, effective management and prognosis of MOH, by summaries and integrates the results and finding in previously performed more than 15000 studies (from the year of 2010 to 2023) available from the scientific database of the University Medical Library in the University Clinical centre of Niš, which aimed to investigate and define a complexcity of this type of headache. Recent finding: It has been proposed that all acute migraine medications can lead to MOH, with differences in the propensity of different agents to cause the problem. Early data suggests that triptans and other pain killers used for the acute treatment of migraine, may be an exception. Recent studies show that practicioners and the general public are still largely unaware of the problem of medication overuse and its damaging effects. Summary: Although it is likely that MOH does occur and restricting the amount of acute medications is necessary to prevent it. It is also possible that increasing amounts of acute medications are simply a reflection of poorly controlled headaches, rather than a couse. Further researches need to be developed to identify more precisious mechanism in MOH effecitive management and its evolution. Key word: medication overuse headache (MOH)
Keywords
medication overuse headache (MOH)
Subject
Medicine and Pharmacology, Neuroscience and Neurology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
