Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Electrocardiographic Characteristics, Identification, and Management of Frequent Premature Ventricular Contractions

Dimitris Tsiachris
* ORCID logo ,
Michail Botis
,
Ioannis Doundoulakis
ORCID logo ,
Lamprini Iro Bartsioka
,
Panagiotis Tsioufis
ORCID logo ,
Athanasios Kordalis
,
Christos-Konstantinos Antoniou
ORCID logo ,
Konstantinos Tsioufis
,
Konstantinos A Gatzoulis
ORCID logo
Version 1 : Received: 9 September 2023 / Approved: 12 September 2023 / Online: 12 September 2023 (08:53:41 CEST)

A peer-reviewed article of this Preprint also exists.

Tsiachris, D.; Botis, M.; Doundoulakis, I.; Bartsioka, L.I.; Tsioufis, P.; Kordalis, A.; Antoniou, C.-K.; Tsioufis, K.; Gatzoulis, K.A. Electrocardiographic Characteristics, Identification, and Management of Frequent Premature Ventricular Contractions. Diagnostics 2023, 13, 3094. Tsiachris, D.; Botis, M.; Doundoulakis, I.; Bartsioka, L.I.; Tsioufis, P.; Kordalis, A.; Antoniou, C.-K.; Tsioufis, K.; Gatzoulis, K.A. Electrocardiographic Characteristics, Identification, and Management of Frequent Premature Ventricular Contractions. Diagnostics 2023, 13, 3094.

Abstract

Premature ventricular complexes (PVCs) are frequently encountered in clinical practice. The association of PVCs with adverse cardiovascular outcomes in the context of structural heart disease is well established, yet the association between PVCs and cardiovascular outcomes in the absence of structural heart disease is not fully elucidated. Cardiac magnetic resonance (CMR) seems to contribute prognostically in the latter subgroup. PVC- induced myocardial dysfunction refers to the impairment of ventricular function due to the PVCs and is mainly associated with a PVC burden greater than 10%. The surface 12- lead ECG is used to localize the anatomic site of origin and multiple algorithms have been developed to differentiate right ventricular and left ventricular outflow tract (RVOT and LVOT, respectively) origin. Novel algorithms include alternative ECG configurations and lately, sophisticated artificial intelligence methods have been utilized to distinguish the origins of outflow tract arrhythmias. The decision to therapeutically address PVCs should be taken upon the presence of symptoms or the development of PVC- induced myocardial dysfunction. The therapeutic modalities include pharmacological therapy, namely I-C antiarrhythmic drugs and beta blockers, as well as catheter ablation, which demonstrates superior efficacy and safety.

Keywords

premature ventricular contractions; catheter ablation; electrocardiography; management algorithm

Subject

Medicine and Pharmacology, Cardiac and Cardiovascular Systems

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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