Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Title Mature Triphyllic Cystic Teratoma of the Posterior Mediastinum in a Fetus: A Case Report and Literature Review

Version 1 : Received: 4 September 2023 / Approved: 5 September 2023 / Online: 6 September 2023 (03:22:52 CEST)
Version 2 : Received: 8 September 2023 / Approved: 11 September 2023 / Online: 11 September 2023 (10:14:07 CEST)
Version 3 : Received: 14 September 2023 / Approved: 15 September 2023 / Online: 18 September 2023 (07:14:56 CEST)

A peer-reviewed article of this Preprint also exists.

Salzillo, C.; Quaranta, A.; De Biasi, G.; Cazzato, G.; Serio, G.; Vimercati, A.; Nicolì, P.; Resta, L.; Marzullo, A. Mature Triphyllic Cystic Teratoma of the Posterior Mediastinum in a Fetus: A Case Report and Literature Review. Diseases 2023, 11, 144. Salzillo, C.; Quaranta, A.; De Biasi, G.; Cazzato, G.; Serio, G.; Vimercati, A.; Nicolì, P.; Resta, L.; Marzullo, A. Mature Triphyllic Cystic Teratoma of the Posterior Mediastinum in a Fetus: A Case Report and Literature Review. Diseases 2023, 11, 144.

Abstract

A teratoma is a neoplasm composed of cell populations or tissues that remind, in their appearance, normal elements derived from at least two embryonic layers. Fetal mature teratomas are normally benign, cystic, and typically occur along the midline, while they are rare in the posterior mediastinum. Teratomas are frequently solitary, however they may sometimes be associated with other congenital anomalies and/or with chromosomal abnormalities. Clinically, they are often asymptomatic but can occasionally cause compression symptoms. Prenatal diagnoses are uncommon and made with ultrasonography; differential diagnosis with other congenital conditions is mandatory. We report the case of a 21 weeks of gestational age-old fetus with a Mature Triphyllic Fetal Cystic Teratoma, grade 0, located in the right posterior mediastinum.

Keywords

mature triphyllic cystic teratoma; posterior mediastinum; fetal teratoma; germ cell tumor; prenatal diagnosis

Subject

Medicine and Pharmacology, Oncology and Oncogenics

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