Messire, G.; Ferreira, V.; Caillet, E.; Bodin, L.; Auville, A.; Berteina-Raboin, S. Sabinene: A New Green Solvent Used in the Synthesis of Thiazolo[5,4-b]pyridines by Thermal or Microwave Activation. Molecules2023, 28, 6924.
Messire, G.; Ferreira, V.; Caillet, E.; Bodin, L.; Auville, A.; Berteina-Raboin, S. Sabinene: A New Green Solvent Used in the Synthesis of Thiazolo[5,4-b]pyridines by Thermal or Microwave Activation. Molecules 2023, 28, 6924.
Messire, G.; Ferreira, V.; Caillet, E.; Bodin, L.; Auville, A.; Berteina-Raboin, S. Sabinene: A New Green Solvent Used in the Synthesis of Thiazolo[5,4-b]pyridines by Thermal or Microwave Activation. Molecules2023, 28, 6924.
Messire, G.; Ferreira, V.; Caillet, E.; Bodin, L.; Auville, A.; Berteina-Raboin, S. Sabinene: A New Green Solvent Used in the Synthesis of Thiazolo[5,4-b]pyridines by Thermal or Microwave Activation. Molecules 2023, 28, 6924.
Abstract
Following on from work already carried out in our laboratory on a new biomass-derived green solvent, eucalyptol, we are now turning our attention to sabinene as a new green solvent. Sabinene is also derived from biomass. We have shown that it can be used as such or distilled to synthesize thiazolo[5,4-b]pyridine heterocycles by thermal or microwave activation. This new solvent was compared with various conventional and green solvents. The conditions were optimized to enable us to carry out the syntheses in good yields, and we were able to show that sabinene, a natural bicyclic monoterpene, could be used effectively as a solvent.
Keywords
Sustainable chemistry; Bicyclic N,S-heterocycles; Biomass-based Green Solvents; Sabinene.
Subject
Chemistry and Materials Science, Organic Chemistry
Copyright:
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