Anti-Cancer Properties of Flax Seed Proteome

Yulia Merkher; Elizaveta Kontareva; Anastasia Alexandrova; RAJESHA JAVARAIAH; Margarita Pustovalova; Sergey Leonov

doi:10.20944/preprints202308.2063.v1

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preprints.org > biology and life sciences > biochemistry and molecular biology > doi: 10.20944/preprints202308.2063.v1

Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Anti-Cancer Properties of Flax Seed Proteome

Yulia Merkher

^* ,

Elizaveta Kontareva

Anastasia Alexandrova

RAJESHA JAVARAIAH

Margarita Pustovalova

Sergey Leonov

Version 1 : Received: 30 August 2023 / Approved: 30 August 2023 / Online: 31 August 2023 (03:54:42 CEST)

A peer-reviewed article of this Preprint also exists.

Merkher, Y.; Kontareva, E.; Alexandrova, A.; Javaraiah, R.; Pustovalova, M.; Leonov, S. Anti-Cancer Properties of Flaxseed Proteome. Proteomes 2023, 11, 37. Merkher, Y.; Kontareva, E.; Alexandrova, A.; Javaraiah, R.; Pustovalova, M.; Leonov, S. Anti-Cancer Properties of Flaxseed Proteome. Proteomes 2023, 11, 37.

Abstract

Flaxseed has been recognized as a valuable source of nutrients and bioactive compounds, including proteins that possess various health benefits. In recent years, studies have shown that flaxseed proteins, including albumins, globulins, glutelin, and prolamins, possess anti-cancer properties. These properties are attributed to their ability to inhibit cancer cell proliferation, induce apoptosis, and interfere with cancer cell signaling pathways, ultimately leading to the inhibition of metastasis. Moreover, flaxseed proteins have been reported to modulate cancer cell mechanobiology, leading to changes in cell behavior and reduced cancer cell migration and invasion. This review provides an overview of the anti-cancer properties of flaxseed proteins, with a focus on their potential use in cancer treatment. Additionally, it highlights the need for further research to fully establish the potential of flaxseed proteins in cancer therapy.

Keywords

metastasis; flaxseed proteins; cancer treatment; radiotherapy; mechanobiology; proteoform level analysis; flaxseed amino-acids

Subject

Biology and Life Sciences, Biochemistry and Molecular Biology

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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