Nguena-Dongue, B.; Pone Kamdem, B.; Keilah Lunga, P.; Fekam Boyom, F. Ethnomedicinal Uses, Phytochemistry, and Pharmacological Activity of the Irvingia Species. Preprints2023, 2023081834. https://doi.org/10.20944/preprints202308.1834.v1
APA Style
Nguena-Dongue, B., Pone Kamdem, B., Keilah Lunga, P., & Fekam Boyom, F. (2023). Ethnomedicinal Uses, Phytochemistry, and Pharmacological Activity of the <em>Irvingia</em> Species. Preprints. https://doi.org/10.20944/preprints202308.1834.v1
Chicago/Turabian Style
Nguena-Dongue, B., Paul Keilah Lunga and Fabrice Fekam Boyom. 2023 "Ethnomedicinal Uses, Phytochemistry, and Pharmacological Activity of the <em>Irvingia</em> Species" Preprints. https://doi.org/10.20944/preprints202308.1834.v1
Abstract
Plants belonging to the genus Irvingia are widespread across the African and Southeast Asian regions of the world. Irvingia gabonensis, Irvingia malayana, and Irvingia grandifolia are among the commonly used species in ethnomedicine, especially in Africa. Fever, scabies, toothache, inflammation, and liver and gastrointestinal disorders are among the pathological conditions that are reverted by Irvingia plants upon traditional preparations. Modern pharmacological investigations have substantiated the ethnomedicinal uses of Irvingia spp. Reports on the phytochemical analysis of Irvingia plants have revealed the presence of a number of secondary metabolites, such as flavonoids, phenolic compounds, tannins, saponins and alkaloids. Based on the foregoing, the present study provides a comprehensive evaluation of reports on the ethnomedicinal use, phytochemistry, pharmacology, and toxicity of plants from the genus Irvingia. Relevant information on Irvingia plants was mostly obtained from major scientific databases from their inception until July 2023. As a result, more than forty compounds have been identified in Irvingia spp. proving the abundance of secondary metabolites in these plants. Reports have pointed out modern pharmacological activities, such as antiprotozoal, antimicrobial, antioxidant, antidiabetic, anti-inflammatory, and hepatoprotective activities. The present study provides more insights for the successful utilization of Irvingia plants and may guide further research on their therapeutic potential in the treatment of various diseases.
Medicine and Pharmacology, Pharmacology and Toxicology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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