Rhabdomyolysis in BA.5 and BA.4 SARS-COV2 Variants: A Single Center Experience

How to cite: Capoluongo, N.; Mascolo, A.; Tiberio, C.; Sarno, M.; Somma, G.; Raffone, M.; Di Spirito, A.; Minei, G.; Pisapia, R.; Pomicino, A.; Di Micco, P.; Capuano, A.; Perrella, A. Rhabdomyolysis in BA.5 and BA.4 SARS-COV2 Variants: A Single Center Experience. Preprints 2023, 2023081489. https://doi.org/10.20944/preprints202308.1489.v1 Capoluongo, N.; Mascolo, A.; Tiberio, C.; Sarno, M.; Somma, G.; Raffone, M.; Di Spirito, A.; Minei, G.; Pisapia, R.; Pomicino, A.; Di Micco, P.; Capuano, A.; Perrella, A. Rhabdomyolysis in BA.5 and BA.4 SARS-COV2 Variants: A Single Center Experience. Preprints 2023, 2023081489. https://doi.org/10.20944/preprints202308.1489.v1

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MDPI and ACS Style

Capoluongo, N.; Mascolo, A.; Tiberio, C.; Sarno, M.; Somma, G.; Raffone, M.; Di Spirito, A.; Minei, G.; Pisapia, R.; Pomicino, A.; Di Micco, P.; Capuano, A.; Perrella, A. Rhabdomyolysis in BA.5 and BA.4 SARS-COV2 Variants: A Single Center Experience. Preprints 2023, 2023081489. https://doi.org/10.20944/preprints202308.1489.v1

APA Style

Capoluongo, N., Mascolo, A., Tiberio, C., Sarno, M., Somma, G., Raffone, M., Di Spirito, A., Minei, G., Pisapia, R., Pomicino, A., Di Micco, P., Capuano, A., & Perrella, A. (2023). Rhabdomyolysis in BA.5 and BA.4 SARS-COV2 Variants: A Single Center Experience. Preprints. https://doi.org/10.20944/preprints202308.1489.v1

Chicago/Turabian Style

Capoluongo, N., Annalisa Capuano and Alessandro Perrella. 2023 "Rhabdomyolysis in BA.5 and BA.4 SARS-COV2 Variants: A Single Center Experience" Preprints. https://doi.org/10.20944/preprints202308.1489.v1

Abstract

Rhabdomyolysis is a serious clinical condition, which if left untreated can lead to kidney failure and in extreme cases, to death. It has also been reported in association with SARS COV2 infection and can be its initial presentation. COVID-19 is a disease caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2), which has many variants that change the characteristics of the disease affecting, among other things, the method of transmission or treatment. Some investigators have implicated excessive immune response in the causes of muscle damage during SARS-CoV-2 infection. Others point to direct damage caused by the virus or involving immune factors. In this study we described cases of COVID-19 infection from 1 June 2022 to 15 July 2022 with elevated muscle enzymes in the blood and hospitalized to the first division of Cotugno hospital in Campania. Of 39 patients with SARS-CoV-2 infection, 15 patients presented also rhabdomyolysis. The most common symptoms were: asthenia, fever, arthomyalgia, lipothymia and syncope. No patient had myocardial infarction and 2 patients had atrial fibrillation. All patients were affected by omicron SARS-CoV-2 variants. Of these patients: 4 patients died (2 due to rhabdomyolysis and 2 due to sepsis) and only one patient presented acute kidney injury.

Keywords

COVID-19; Rhabdomyolisys; Viruses; SARS-COV-2

Subject

Medicine and Pharmacology, Epidemiology and Infectious Diseases

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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