Zhang, J.; Zheng, Y.; Martens, L.; Pfeiffer, A.F.H. The Regulation and Secretion of Glucagon in Response to Nutrient Composition: Unraveling Their Intricate Mechanisms. Nutrients2023, 15, 3913.
Zhang, J.; Zheng, Y.; Martens, L.; Pfeiffer, A.F.H. The Regulation and Secretion of Glucagon in Response to Nutrient Composition: Unraveling Their Intricate Mechanisms. Nutrients 2023, 15, 3913.
Zhang, J.; Zheng, Y.; Martens, L.; Pfeiffer, A.F.H. The Regulation and Secretion of Glucagon in Response to Nutrient Composition: Unraveling Their Intricate Mechanisms. Nutrients2023, 15, 3913.
Zhang, J.; Zheng, Y.; Martens, L.; Pfeiffer, A.F.H. The Regulation and Secretion of Glucagon in Response to Nutrient Composition: Unraveling Their Intricate Mechanisms. Nutrients 2023, 15, 3913.
Abstract
In the context of type 2 diabetes (T2DM), fasting and postprandial hyperglucagonemia have long been linked to the disease's development and progression. However, recent studies have brought to light the positive impact of glucagon-agonists on lipid metabolism and energy homeostasis. This review delves into the intricate relationship and underlying mechanisms between glucagon and nutrient composition, which may hold promise in devising novel therapeutic approaches for T2DM management.
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