Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Biocompatible and Biomimetic Minerals Serum Can Reverse Dental Erosion and Improve Tooth Shade Variation.

Version 1 : Received: 16 August 2023 / Approved: 17 August 2023 / Online: 18 August 2023 (08:12:54 CEST)

How to cite: D’Agostino, S.; Valentini, G.; Rafique, J.; Dolci, M. Biocompatible and Biomimetic Minerals Serum Can Reverse Dental Erosion and Improve Tooth Shade Variation.. Preprints 2023, 2023081288. https://doi.org/10.20944/preprints202308.1288.v1 D’Agostino, S.; Valentini, G.; Rafique, J.; Dolci, M. Biocompatible and Biomimetic Minerals Serum Can Reverse Dental Erosion and Improve Tooth Shade Variation.. Preprints 2023, 2023081288. https://doi.org/10.20944/preprints202308.1288.v1

Abstract

Enamel erosion is a process which happens every time we eat and it may be accelerated by some particular acid foods, drinks or other agents. Dental enamel when damaged by low pH substances becomes chalky, rough, opaque, yellowed and it can be related to dentinal hypersensitivity. To the present day, several possible solutions are available, therefore the aim of this study was to evaluate the effect of a biocompatible minerals serum based on calcium silicate, sodium phosphate and fluoride (Regenerate™) on the damaged enamel by four different acid liquids. 135 ovine teeth were equally divided into 5 groups and submerged for one week into lemon juice, energy drink, coffee, tea and physiologic solution for the negative control. The first 4 groups were evaluated for their color with an analogical color scale (Vita® Scale) and for their surface assigning a qualitative aspect among opaque, rough, chalky or smooth. Then they were treated with hydroxyapatite gels and re-evaluated for the same parameters. Data were checked for the normal distribution with Shapiro-Wilk test and analyzed with dependent t-test or Wilcoxon Signed Rank test, every test with a p≤0.05. Both color and surface aspect showed a strongly significant improvement after the treatment. Biocompatible minerals serum based on hydroxyapatite is able to reverse teeth erosion, improve the color and restore the smoothness of the dental enamel.

Keywords

biocompatible minerals; calcium silicate sodium phosphate; enamel; Erosion; hydroxyapatite; remineralization

Subject

Medicine and Pharmacology, Dentistry and Oral Surgery

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