Version 1
: Received: 15 August 2023 / Approved: 15 August 2023 / Online: 15 August 2023 (11:49:25 CEST)
How to cite:
Diederich, S.; Babiuk, S.; Boshra, H. A Survey Of Henipavirus Tropism—Our Current Understanding From A Species/Organ And Cellular Level. Preprints2023, 2023081127. https://doi.org/10.20944/preprints202308.1127.v1
Diederich, S.; Babiuk, S.; Boshra, H. A Survey Of Henipavirus Tropism—Our Current Understanding From A Species/Organ And Cellular Level. Preprints 2023, 2023081127. https://doi.org/10.20944/preprints202308.1127.v1
Diederich, S.; Babiuk, S.; Boshra, H. A Survey Of Henipavirus Tropism—Our Current Understanding From A Species/Organ And Cellular Level. Preprints2023, 2023081127. https://doi.org/10.20944/preprints202308.1127.v1
APA Style
Diederich, S., Babiuk, S., & Boshra, H. (2023). A Survey Of Henipavirus Tropism—Our Current Understanding From A Species/Organ And Cellular Level. Preprints. https://doi.org/10.20944/preprints202308.1127.v1
Chicago/Turabian Style
Diederich, S., Shawn Babiuk and Hani Boshra. 2023 "A Survey Of Henipavirus Tropism—Our Current Understanding From A Species/Organ And Cellular Level" Preprints. https://doi.org/10.20944/preprints202308.1127.v1
Abstract
Henipaviruses are single-stranded RNA viruses that have been shown to be virulent in several species including humans, pigs, horses, and rodents. Isolated nearly 30 years ago, these viruses have been shown to be of particular concern to public health, as at least two members (Nipah and Hendra viruses) are highly virulent, as well as zoonotic, and are thus classified as BSL4 pathogens. Although only 5 members of this genus have been isolated and characterized, metagenomics analysis using animal fluids and tissues has demonstrated the existence of other novel henipaviruses, suggesting a far greater degree of phylogenetic diversity than currently known. Using a variety of molecular biology techniques, it has been shown that these viruses exhibit varying degrees of tropism, on a species, organ/tissue, and cellular level. This review will attempt to provide a general overview of our current understanding of henipaviruses, with particular emphasis on viral tropism.
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
