Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Southern European Atlantic Diet and Its Supplements: Chemical Bases of Its Anticancer Properties

Version 1 : Received: 13 August 2023 / Approved: 14 August 2023 / Online: 14 August 2023 (09:49:55 CEST)

A peer-reviewed article of this Preprint also exists.

Vivanco, P.G.; Taboada, P.; Coelho, A. The Southern European Atlantic Diet and Its Supplements: The Chemical Bases of Its Anticancer Properties. Nutrients 2023, 15, 4274. Vivanco, P.G.; Taboada, P.; Coelho, A. The Southern European Atlantic Diet and Its Supplements: The Chemical Bases of Its Anticancer Properties. Nutrients 2023, 15, 4274.

Abstract

Scientific evidence increasingly supports the strong link between diet and health, acknowledging that a well-balanced diet plays a crucial role in preventing chronic diseases such as obesity, diabetes, cardiovascular issues, and certain types of cancer. This perspective opens the door to developing precision diets, particularly tailored for individuals at risk of developing cancer. It encompasses a vast research area and involves the study of an expanding array of compounds with multi-level "omics" compositions, including genomics, transcriptomics, proteomics, epigenomics, miRNomics, and metabolomics. We review here the components of the Southern European Atlantic Diet (SEAD) from both a chemical and pharmacological standpoint. The information sources consulted, complemented by crystallographic data from the Protein Data Bank, establish a direct link between SEAD and its anticancer properties. The data collected strongly suggest that SEAD offers an exceptionally healthy profile, particularly due to the presence of beneficial biomolecules in its foods. The inclusion of olive oil and paprika in this diet provides numerous health benefits, and science supports the anti-cancer properties of dietary supplements with biomolecules sourced from vegetables of the brassica genus. Nonetheless, further research is warranted in this field to gain deeper insights into the potential benefits of SEAD's bioactive compounds against cancer.

Keywords

Southern Atlantic Diet; Anticancer; glucosinolates; sulforaphane; phenolic compounds; flavonoids; antioxidant; chemoprevention; nutragenomic; nutraceutical

Subject

Biology and Life Sciences, Food Science and Technology

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