Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Long-Term Efficacy of Chlorhexidine Gel in Single Crown Implant Rehabilitation: A Five-Year Follow-Up Study

Gianmaria D’Addazio
,
Eugenio Manciocchi
ORCID logo ,
Giuseppe Tafuri
,
Ruggero Schiavone
,
Giovanna Murmura
,
Luan Mavriqi
,
Bruna Sinjari
* ORCID logo ,
Sergio Caputi
Version 1 : Received: 8 August 2023 / Approved: 9 August 2023 / Online: 10 August 2023 (09:09:13 CEST)

A peer-reviewed article of this Preprint also exists.

D’Addazio, G.; Manciocchi, E.; Tafuri, G.; Schiavone, R.; Murmura, G.; Mavriqi, L.; Sinjari, B.; Caputi, S. Long-Term Efficacy of Chlorhexidine Gel in Single-Crown Implant Rehabilitation: A Five-Year Follow-Up Study. Dent. J. 2023, 11, 228. D’Addazio, G.; Manciocchi, E.; Tafuri, G.; Schiavone, R.; Murmura, G.; Mavriqi, L.; Sinjari, B.; Caputi, S. Long-Term Efficacy of Chlorhexidine Gel in Single-Crown Implant Rehabilitation: A Five-Year Follow-Up Study. Dent. J. 2023, 11, 228.

Abstract

Chlorhexidine digluconate (CHX) has shown the ability to significantly reduce inflammation and marginal bone loss (MBL) at 1-year follow-up but limited data exists regarding its long-term efficacy in peri implant stability. The objective was to compare the long-term effects of a placebo gel (16 patients in Group A) or a 0.20% CHX gel (15 patients in Group B) used at each previous surgical and prosthetic stage. Follow-ups were conducted in 2022, investigating by biological, radiological, clinical, mechanical evaluation the long-term effects. Data were statistically analyzed. The research achieved a 96.7% implant success rate over five years, but 41.9% of patients didn't attend annual oral hygiene check-ups. The average MBL was 1.04 ± 0.39 mm, with no significant differences between the two groups. Notably, patients who attended regular periodontal check-ups experienced significantly less MBL than those who didn't (p <0.05). At five years, the effects of CHX were reduced, with both groups showing moderate bone loss. The results suggest early disinfection could enhance both short and long-term outcomes. In fact, patient with initial minor MBL preserve this advantage also at 5 years of follow-up. Additionally, the data underscore the importance of annual check-ups in early detection and management of biological and mechanical complications.

Keywords

Chlorhexidine Gel; marginal bone loss; Peri-implantitis; implant survival rate; implant decontamination; dental implant complication.

Subject

Medicine and Pharmacology, Dentistry and Oral Surgery

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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