Cell-Tissue Interaction: The Biomimetic Approach to Design Tissue Engineered Biomaterials

Paola Nitti; Athira Narayanan; Rebecca Pellegrino; Stefania Villani; Marta Madaghiele; Christian Demitri

doi:10.20944/preprints202308.0491.v1

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preprints.org > engineering > bioengineering > doi: 10.20944/preprints202308.0491.v1

Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Cell-Tissue Interaction: The Biomimetic Approach to Design Tissue Engineered Biomaterials

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These authors contributed equally to the work.

Version 1 : Received: 5 August 2023 / Approved: 7 August 2023 / Online: 7 August 2023 (07:26:41 CEST)

A peer-reviewed article of this Preprint also exists.

Nitti, P.; Narayanan, A.; Pellegrino, R.; Villani, S.; Madaghiele, M.; Demitri, C. Cell-Tissue Interaction: The Biomimetic Approach to Design Tissue Engineered Biomaterials. Bioengineering 2023, 10, 1122. Nitti, P.; Narayanan, A.; Pellegrino, R.; Villani, S.; Madaghiele, M.; Demitri, C. Cell-Tissue Interaction: The Biomimetic Approach to Design Tissue Engineered Biomaterials. Bioengineering 2023, 10, 1122.

Abstract

The advancements achieved in Tissue Engineering are based on a careful and in-depth study of cell-tissue interaction. The choice of a certain biomaterial in Tissue Engineering is fundamental as it represents an interface for adherent cells in the creation of a microenvironment suitable for cell growth and differentiation. The knowledge of the biochemical and biophysical properties of the extracellular matrix is a useful tool for the optimization of polymeric scaffolds. The aim of this re-view is to analyse the chemical, physical and biological parameters on which it is possible to act in Tissue Engineering for the optimization of polymeric scaffolds. Understanding the scaffold impact on cell fate is of paramount importance for the successful advancement of Tissue Engineering.

Keywords

Extracellular matrix; Cell-tissue interactions; Tissue engineering; Regenerative medicine; scaffolds

Subject

Engineering, Bioengineering

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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