Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

The Effects of a 12-Month Dried Plum Consumption on Bone Mineral Density and Bone Turnover Markers in Korean Postmenopausal Women with Osteopenia: A Randomized, Open-Labeled, Controlled Study

Version 1 : Received: 3 August 2023 / Approved: 4 August 2023 / Online: 7 August 2023 (09:28:11 CEST)
Version 2 : Received: 15 August 2023 / Approved: 30 August 2023 / Online: 31 August 2023 (09:03:01 CEST)

How to cite: Yoo, J.; Je, M.; Kim, Y.; Clifton, P.M. The Effects of a 12-Month Dried Plum Consumption on Bone Mineral Density and Bone Turnover Markers in Korean Postmenopausal Women with Osteopenia: A Randomized, Open-Labeled, Controlled Study. Preprints 2023, 2023080457. https://doi.org/10.20944/preprints202308.0457.v1 Yoo, J.; Je, M.; Kim, Y.; Clifton, P.M. The Effects of a 12-Month Dried Plum Consumption on Bone Mineral Density and Bone Turnover Markers in Korean Postmenopausal Women with Osteopenia: A Randomized, Open-Labeled, Controlled Study. Preprints 2023, 2023080457. https://doi.org/10.20944/preprints202308.0457.v1

Abstract

Consumption of prunes has been shown to slow bone loss after menopause in American women but there is no data on its effects in Asian women. 135 postmenopausal Korean women with osteopenia were randomized to 100g/day of prunes or no prunes with 600U vitamin D and 600mg of calcium for 12 months. Bone density was measured at baseline and 12 months in the lumbar spine, both hips and the L forearm. Serum levels of CTX and P1NP and vitamin D calcium and phosphate were measured at baseline, 6 and 12 months. PTH was measured at baseline if vitamin D was low Four women dropped out of each group over the 12 months. There was no difference between groups in blood measures or bone density in any region over the 12 month trial., In conclusion 100g/day of prunes has no effect in Korean woman on bone density or bone markers.

Keywords

bone density; DXA; PTX; P1NP; prunes; women

Subject

Medicine and Pharmacology, Endocrinology and Metabolism

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